Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark

In this research, the bark extract of the yew (Taxus baccata L.) tree trunk grow in AfraTakhte forest cache of Aliabad-e Katul) located in Golestan province was extracted with acetone solvent and by Soxhlet apparatus method and then the chemical components within it were identified. The bark of prep...

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Autores principales:	Seddigheh Afraz, Seyyed Khalil Hosseinihashemi
Formato:	article
Lenguaje:	FA
Publicado:	Regional Information Center for Science and Technology (RICeST) 2018
Materias:	Yew bark acetone extract cytotoxic and anticancer components Forestry SD1-669.5
Acceso en línea:	https://doaj.org/article/67b34b6786db4f52837273b97b2c5a94
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spelling	oai:doaj.org-article:67b34b6786db4f52837273b97b2c5a942021-12-02T02:20:06ZExtraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark1735-09132383-112X10.22092/ijwpr.2017.115389.1436https://doaj.org/article/67b34b6786db4f52837273b97b2c5a942018-03-01T00:00:00Zhttp://ijwpr.areeo.ac.ir/article_115141_fd75382e716b1296812a537298ab5da5.pdfhttps://doaj.org/toc/1735-0913https://doaj.org/toc/2383-112XIn this research, the bark extract of the yew (Taxus baccata L.) tree trunk grow in AfraTakhte forest cache of Aliabad-e Katul) located in Golestan province was extracted with acetone solvent and by Soxhlet apparatus method and then the chemical components within it were identified. The bark of prepared disks was separated and converted to the flour. Afterwards, extract insoluble acetone solvent was prepared according to TAPPI standard method. In order to silylation of compounds, amount of dry powder of extract was poured into a glass vial and the derivative materials (pyridine, BSTFA + TMCS 1%) were added to it and to identification the sample was injected to the gas chromatography- mass spectrometry device. The results from this research indicated that the mean value of acetone extract of yew bark was 13.63%. Generally, 46 compounds were identified in the yew bark. The most abundant identified compounds were including: tetrasiloxane, decamethyl- (14.80%), hexadecanoic acid, hydroxy ester (11.24%), 3-(3-aminopropyl)-6-(3,3-dimethylallylamino)purine (9.85%), d-ribofuranose, 1,2,3,5-tetrakis-O-(hydroxy)- (9.31%), 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one (6.73%). The various chemical components such as phenolic, flavenoid, alkaloid, fatty acid, fatty acid ester, sugar, alkane, fatty alcohol, alcoholic sugar, and stroied were identified in the acetone extract of yew bark that some of them can synthesized as preservatives for inhibition of wood-degrading organisms. The most important identified cytotoxic and anticancer compounds in the acetone extract of yew bark has been 4-piperidinone, 2,2,6,6-tetramethyl- (0.19%) and phenol, 2,4-bis(1,1-dimethylethy)- (3.32%).Seddigheh AfrazSeyyed Khalil HosseinihashemiRegional Information Center for Science and Technology (RICeST)articleYew barkacetone extractcytotoxic and anticancer componentsForestrySD1-669.5FAتحقیقات علوم چوب و کاغذ ایران, Vol 33, Iss 1, Pp 88-99 (2018)
institution	DOAJ
collection	DOAJ
language	FA
topic	Yew bark acetone extract cytotoxic and anticancer components Forestry SD1-669.5
spellingShingle	Yew bark acetone extract cytotoxic and anticancer components Forestry SD1-669.5 Seddigheh Afraz Seyyed Khalil Hosseinihashemi Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark
description	In this research, the bark extract of the yew (Taxus baccata L.) tree trunk grow in AfraTakhte forest cache of Aliabad-e Katul) located in Golestan province was extracted with acetone solvent and by Soxhlet apparatus method and then the chemical components within it were identified. The bark of prepared disks was separated and converted to the flour. Afterwards, extract insoluble acetone solvent was prepared according to TAPPI standard method. In order to silylation of compounds, amount of dry powder of extract was poured into a glass vial and the derivative materials (pyridine, BSTFA + TMCS 1%) were added to it and to identification the sample was injected to the gas chromatography- mass spectrometry device. The results from this research indicated that the mean value of acetone extract of yew bark was 13.63%. Generally, 46 compounds were identified in the yew bark. The most abundant identified compounds were including: tetrasiloxane, decamethyl- (14.80%), hexadecanoic acid, hydroxy ester (11.24%), 3-(3-aminopropyl)-6-(3,3-dimethylallylamino)purine (9.85%), d-ribofuranose, 1,2,3,5-tetrakis-O-(hydroxy)- (9.31%), 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one (6.73%). The various chemical components such as phenolic, flavenoid, alkaloid, fatty acid, fatty acid ester, sugar, alkane, fatty alcohol, alcoholic sugar, and stroied were identified in the acetone extract of yew bark that some of them can synthesized as preservatives for inhibition of wood-degrading organisms. The most important identified cytotoxic and anticancer compounds in the acetone extract of yew bark has been 4-piperidinone, 2,2,6,6-tetramethyl- (0.19%) and phenol, 2,4-bis(1,1-dimethylethy)- (3.32%).
format	article
author	Seddigheh Afraz Seyyed Khalil Hosseinihashemi
author_facet	Seddigheh Afraz Seyyed Khalil Hosseinihashemi
author_sort	Seddigheh Afraz
title	Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark
title_short	Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark
title_full	Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark
title_fullStr	Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark
title_full_unstemmed	Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark
title_sort	extraction and identification of chemical composition within acetone extract of taxus baccata l. bark
publisher	Regional Information Center for Science and Technology (RICeST)
publishDate	2018
url	https://doaj.org/article/67b34b6786db4f52837273b97b2c5a94
work_keys_str_mv	AT seddighehafraz extractionandidentificationofchemicalcompositionwithinacetoneextractoftaxusbaccatalbark AT seyyedkhalilhosseinihashemi extractionandidentificationofchemicalcompositionwithinacetoneextractoftaxusbaccatalbark
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Extraction and Identification of Chemical Composition within Acetone Extract of Taxus baccata L. Bark

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