In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A

Bioactive coatings offer a strategy to modulate host response to implants, but their translation to the clinic is hampered by their fast in vivo degradation. Here, the authors use an engineered bacterial protein to regenerate an anti-thrombogenic film in vitro and in situafter device implantation.

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Autores principales:	Hyun Ok Ham, Zheng Qu, Carolyn A. Haller, Brent M. Dorr, Erbin Dai, Wookhyun Kim, David R. Liu, Elliot L. Chaikof
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/67c96988069c478296613a074a5dbf5b
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spelling	oai:doaj.org-article:67c96988069c478296613a074a5dbf5b2021-12-02T14:39:49ZIn situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A10.1038/ncomms111402041-1723https://doaj.org/article/67c96988069c478296613a074a5dbf5b2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11140https://doaj.org/toc/2041-1723Bioactive coatings offer a strategy to modulate host response to implants, but their translation to the clinic is hampered by their fast in vivo degradation. Here, the authors use an engineered bacterial protein to regenerate an anti-thrombogenic film in vitro and in situafter device implantation.Hyun Ok HamZheng QuCarolyn A. HallerBrent M. DorrErbin DaiWookhyun KimDavid R. LiuElliot L. ChaikofNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hyun Ok Ham Zheng Qu Carolyn A. Haller Brent M. Dorr Erbin Dai Wookhyun Kim David R. Liu Elliot L. Chaikof In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
description	Bioactive coatings offer a strategy to modulate host response to implants, but their translation to the clinic is hampered by their fast in vivo degradation. Here, the authors use an engineered bacterial protein to regenerate an anti-thrombogenic film in vitro and in situafter device implantation.
format	article
author	Hyun Ok Ham Zheng Qu Carolyn A. Haller Brent M. Dorr Erbin Dai Wookhyun Kim David R. Liu Elliot L. Chaikof
author_facet	Hyun Ok Ham Zheng Qu Carolyn A. Haller Brent M. Dorr Erbin Dai Wookhyun Kim David R. Liu Elliot L. Chaikof
author_sort	Hyun Ok Ham
title	In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
title_short	In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
title_full	In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
title_fullStr	In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
title_full_unstemmed	In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A
title_sort	in situ regeneration of bioactive coatings enabled by an evolved staphylococcus aureus sortase a
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/67c96988069c478296613a074a5dbf5b
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In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A

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