Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index

Abstract Objectives To investigate common pathogenic bacteria of periodontal diseases (PD) in patients with type 2 diabetes mellitus (T2DM) and its relationship with PD severity, glycemic control and body mass index (BMI). Material and Methods This case–control study consisted of 55 patients with T2...

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Autores principales:	Mojtaba Akherati, Ebrahim Shafaei, Hamid Salehiniya, Hamid Abbaszadeh
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	bacteria body mass index diabetes mellitus periodontal disease periodontal index Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/67d0b485d511458695765d07c9e4fa4d
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spelling	oai:doaj.org-article:67d0b485d511458695765d07c9e4fa4d2021-12-02T12:59:21ZComparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index2057-434710.1002/cre2.453https://doaj.org/article/67d0b485d511458695765d07c9e4fa4d2021-12-01T00:00:00Zhttps://doi.org/10.1002/cre2.453https://doaj.org/toc/2057-4347Abstract Objectives To investigate common pathogenic bacteria of periodontal diseases (PD) in patients with type 2 diabetes mellitus (T2DM) and its relationship with PD severity, glycemic control and body mass index (BMI). Material and Methods This case–control study consisted of 55 patients with T2DM and 55 individuals as control. Samples were collected from periodontal pockets. After DNA extraction, using 16srRNA‐specific primers, the presence of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Prevotella intermedia (Pi), and Fusobacterium nucleatum (Fn) were examined based on polymerase chain reaction method. Results Aa frequency was significantly higher in in T2DM group than control. There were no significant differences in the frequencies of Pg, Tf, Pi, and Fn between studied groups. There were no significant differences between frequencies of studied bacteria in different severities of periodontitis in T2DM group. Prevalence of Tf in T2DM patients with moderate periodontitis was significantly higher than non‐diabetics with moderate periodontitis. There was no significant difference between the frequency of bacteria in diabetics with good and poor glycemic control. There was a significant difference between the frequencies of Pg in T2DM individuals with different BMI levels. Conclusions A higher frequency of detection of Aa was found in diabetic when compared to non‐diabetics. Glycemic control did not affect the frequency distribution of studied bacteria in T2DM. Pg was identified in higher frequency in overweight T2DM patients.Mojtaba AkheratiEbrahim ShafaeiHamid SalehiniyaHamid AbbaszadehWileyarticlebacteriabody mass indexdiabetes mellitusperiodontal diseaseperiodontal indexDentistryRK1-715ENClinical and Experimental Dental Research, Vol 7, Iss 6, Pp 1080-1088 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bacteria body mass index diabetes mellitus periodontal disease periodontal index Dentistry RK1-715
spellingShingle	bacteria body mass index diabetes mellitus periodontal disease periodontal index Dentistry RK1-715 Mojtaba Akherati Ebrahim Shafaei Hamid Salehiniya Hamid Abbaszadeh Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
description	Abstract Objectives To investigate common pathogenic bacteria of periodontal diseases (PD) in patients with type 2 diabetes mellitus (T2DM) and its relationship with PD severity, glycemic control and body mass index (BMI). Material and Methods This case–control study consisted of 55 patients with T2DM and 55 individuals as control. Samples were collected from periodontal pockets. After DNA extraction, using 16srRNA‐specific primers, the presence of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Prevotella intermedia (Pi), and Fusobacterium nucleatum (Fn) were examined based on polymerase chain reaction method. Results Aa frequency was significantly higher in in T2DM group than control. There were no significant differences in the frequencies of Pg, Tf, Pi, and Fn between studied groups. There were no significant differences between frequencies of studied bacteria in different severities of periodontitis in T2DM group. Prevalence of Tf in T2DM patients with moderate periodontitis was significantly higher than non‐diabetics with moderate periodontitis. There was no significant difference between the frequency of bacteria in diabetics with good and poor glycemic control. There was a significant difference between the frequencies of Pg in T2DM individuals with different BMI levels. Conclusions A higher frequency of detection of Aa was found in diabetic when compared to non‐diabetics. Glycemic control did not affect the frequency distribution of studied bacteria in T2DM. Pg was identified in higher frequency in overweight T2DM patients.
format	article
author	Mojtaba Akherati Ebrahim Shafaei Hamid Salehiniya Hamid Abbaszadeh
author_facet	Mojtaba Akherati Ebrahim Shafaei Hamid Salehiniya Hamid Abbaszadeh
author_sort	Mojtaba Akherati
title	Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
title_short	Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
title_full	Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
title_fullStr	Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
title_full_unstemmed	Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
title_sort	comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/67d0b485d511458695765d07c9e4fa4d
work_keys_str_mv	AT mojtabaakherati comparisonofthefrequencyofperiodontalpathogenicspeciesofdiabeticsandnondiabeticsanditsrelationtoperiodontitisseverityglycemiccontrolandbodymassindex AT ebrahimshafaei comparisonofthefrequencyofperiodontalpathogenicspeciesofdiabeticsandnondiabeticsanditsrelationtoperiodontitisseverityglycemiccontrolandbodymassindex AT hamidsalehiniya comparisonofthefrequencyofperiodontalpathogenicspeciesofdiabeticsandnondiabeticsanditsrelationtoperiodontitisseverityglycemiccontrolandbodymassindex AT hamidabbaszadeh comparisonofthefrequencyofperiodontalpathogenicspeciesofdiabeticsandnondiabeticsanditsrelationtoperiodontitisseverityglycemiccontrolandbodymassindex
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Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index

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