Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response

Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response

Existing methods for inflicting cellular heat shock are limited by the time delay in achieving the desired temperature and the spatial precision that can be achieved. Here the authors report a method to induce focused thermal protein damage using plasmonic silver nanoparticles.

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Autores principales: Martin Mistrik, Zdenek Skrott, Petr Muller, Ales Panacek, Lucie Hochvaldova, Katarina Chroma, Tereza Buchtova, Veronika Vandova, Libor Kvitek, Jiri Bartek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/67d69097392d41a296cc051f0474624c
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spelling oai:doaj.org-article:67d69097392d41a296cc051f0474624c2021-12-02T10:48:27ZMicrothermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response10.1038/s41467-021-20989-92041-1723https://doaj.org/article/67d69097392d41a296cc051f0474624c2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20989-9https://doaj.org/toc/2041-1723Existing methods for inflicting cellular heat shock are limited by the time delay in achieving the desired temperature and the spatial precision that can be achieved. Here the authors report a method to induce focused thermal protein damage using plasmonic silver nanoparticles.Martin MistrikZdenek SkrottPetr MullerAles PanacekLucie HochvaldovaKatarina ChromaTereza BuchtovaVeronika VandovaLibor KvitekJiri BartekNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Martin Mistrik
Zdenek Skrott
Petr Muller
Ales Panacek
Lucie Hochvaldova
Katarina Chroma
Tereza Buchtova
Veronika Vandova
Libor Kvitek
Jiri Bartek
Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response
description Existing methods for inflicting cellular heat shock are limited by the time delay in achieving the desired temperature and the spatial precision that can be achieved. Here the authors report a method to induce focused thermal protein damage using plasmonic silver nanoparticles.
format article
author Martin Mistrik
Zdenek Skrott
Petr Muller
Ales Panacek
Lucie Hochvaldova
Katarina Chroma
Tereza Buchtova
Veronika Vandova
Libor Kvitek
Jiri Bartek
author_facet Martin Mistrik
Zdenek Skrott
Petr Muller
Ales Panacek
Lucie Hochvaldova
Katarina Chroma
Tereza Buchtova
Veronika Vandova
Libor Kvitek
Jiri Bartek
author_sort Martin Mistrik
title Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response
title_short Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response
title_full Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response
title_fullStr Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response
title_full_unstemmed Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response
title_sort microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase hsp-p97/vcp response
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/67d69097392d41a296cc051f0474624c
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AT katarinachroma microthermalinducedsubcellulartargetedproteindamageincellsonplasmonicnanosilvermodifiedsurfacesevokesatwophasehspp97vcpresponse
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AT liborkvitek microthermalinducedsubcellulartargetedproteindamageincellsonplasmonicnanosilvermodifiedsurfacesevokesatwophasehspp97vcpresponse
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