Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

Lanthipeptides are a class of cyclic post-translationally modified peptides with potential drug-like properties. Here the authors develop a phage display system by expressing lanthipeptide precursors as C-terminal fusions to the phage M13 coat protein pIII in E. coli along with the heterologous modi...

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Autores principales:	Johannes H. Urban, Markus A. Moosmeier, Tobias Aumüller, Marcus Thein, Tjibbe Bosma, Rick Rink, Katharina Groth, Moritz Zulley, Katja Siegers, Kathrin Tissot, Gert N. Moll, Josef Prassler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6804c6078ad541b2a86a6d200c382069
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spelling	oai:doaj.org-article:6804c6078ad541b2a86a6d200c3820692021-12-02T15:38:32ZPhage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein10.1038/s41467-017-01413-72041-1723https://doaj.org/article/6804c6078ad541b2a86a6d200c3820692017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01413-7https://doaj.org/toc/2041-1723Lanthipeptides are a class of cyclic post-translationally modified peptides with potential drug-like properties. Here the authors develop a phage display system by expressing lanthipeptide precursors as C-terminal fusions to the phage M13 coat protein pIII in E. coli along with the heterologous modifying enzymes.Johannes H. UrbanMarkus A. MoosmeierTobias AumüllerMarcus TheinTjibbe BosmaRick RinkKatharina GrothMoritz ZulleyKatja SiegersKathrin TissotGert N. MollJosef PrasslerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johannes H. Urban Markus A. Moosmeier Tobias Aumüller Marcus Thein Tjibbe Bosma Rick Rink Katharina Groth Moritz Zulley Katja Siegers Kathrin Tissot Gert N. Moll Josef Prassler Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
description	Lanthipeptides are a class of cyclic post-translationally modified peptides with potential drug-like properties. Here the authors develop a phage display system by expressing lanthipeptide precursors as C-terminal fusions to the phage M13 coat protein pIII in E. coli along with the heterologous modifying enzymes.
format	article
author	Johannes H. Urban Markus A. Moosmeier Tobias Aumüller Marcus Thein Tjibbe Bosma Rick Rink Katharina Groth Moritz Zulley Katja Siegers Kathrin Tissot Gert N. Moll Josef Prassler
author_facet	Johannes H. Urban Markus A. Moosmeier Tobias Aumüller Marcus Thein Tjibbe Bosma Rick Rink Katharina Groth Moritz Zulley Katja Siegers Kathrin Tissot Gert N. Moll Josef Prassler
author_sort	Johannes H. Urban
title	Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
title_short	Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
title_full	Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
title_fullStr	Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
title_full_unstemmed	Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
title_sort	phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6804c6078ad541b2a86a6d200c382069
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Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

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