Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

Rhodopsin signalling is triggered by the light-induced isomerization of its 11-cisretinal chromophore. Here, the authors use NMR spectroscopy to define retinal orientation and interactions in the active metarhodopsin II intermediate, proposing a two-stage mechanism for rhodopsin activation.

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Detalles Bibliográficos
Autores principales: Naoki Kimata, Andreyah Pope, Markus Eilers, Chikwado A. Opefi, Martine Ziliox, Amiram Hirshfeld, Ekaterina Zaitseva, Reiner Vogel, Mordechai Sheves, Philip J. Reeves, Steven O. Smith
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/68145e548cf44632bc7c5e853a70c0e6
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