α3 Chains of type V collagen regulate breast tumour growth via glypican-1

Collagen has a role in cancer and is particularly important for breast cancer. Here the authors show that the expression of α3 type V collagen and one of its receptors- glipican-1- in the same cell, contributes to a deregulated growth of breast cancer cells.

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Detalles Bibliográficos
Autores principales: Guorui Huang, Gaoxiang Ge, Valerio Izzi, Daniel S. Greenspan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/68162fa1c464468481e0d534591d2944
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Descripción
Sumario:Collagen has a role in cancer and is particularly important for breast cancer. Here the authors show that the expression of α3 type V collagen and one of its receptors- glipican-1- in the same cell, contributes to a deregulated growth of breast cancer cells.