Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota

Non-circulating, tissue-resident T cells have been reported for non-lymphoid organs, but their characterization and regulation in secondary lymphoid organs (SLO) are still lacking. Here the authors show that age and microbiota both exert SLO-specific effects for the various tissue-resident T cell su...

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Autores principales: Aurélie Durand, Alexandra Audemard-Verger, Vincent Guichard, Raphaël Mattiuz, Arnaud Delpoux, Pauline Hamon, Nelly Bonilla, Matthieu Rivière, Jérôme Delon, Bruno Martin, Cédric Auffray, Alexandre Boissonnas, Bruno Lucas
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6817c7ab4e8648ea9360a32bfd190459
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spelling oai:doaj.org-article:6817c7ab4e8648ea9360a32bfd1904592021-12-02T17:31:57ZProfiling the lymphoid-resident T cell pool reveals modulation by age and microbiota10.1038/s41467-017-02458-42041-1723https://doaj.org/article/6817c7ab4e8648ea9360a32bfd1904592018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02458-4https://doaj.org/toc/2041-1723Non-circulating, tissue-resident T cells have been reported for non-lymphoid organs, but their characterization and regulation in secondary lymphoid organs (SLO) are still lacking. Here the authors show that age and microbiota both exert SLO-specific effects for the various tissue-resident T cell subsets.Aurélie DurandAlexandra Audemard-VergerVincent GuichardRaphaël MattiuzArnaud DelpouxPauline HamonNelly BonillaMatthieu RivièreJérôme DelonBruno MartinCédric AuffrayAlexandre BoissonnasBruno LucasNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aurélie Durand
Alexandra Audemard-Verger
Vincent Guichard
Raphaël Mattiuz
Arnaud Delpoux
Pauline Hamon
Nelly Bonilla
Matthieu Rivière
Jérôme Delon
Bruno Martin
Cédric Auffray
Alexandre Boissonnas
Bruno Lucas
Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
description Non-circulating, tissue-resident T cells have been reported for non-lymphoid organs, but their characterization and regulation in secondary lymphoid organs (SLO) are still lacking. Here the authors show that age and microbiota both exert SLO-specific effects for the various tissue-resident T cell subsets.
format article
author Aurélie Durand
Alexandra Audemard-Verger
Vincent Guichard
Raphaël Mattiuz
Arnaud Delpoux
Pauline Hamon
Nelly Bonilla
Matthieu Rivière
Jérôme Delon
Bruno Martin
Cédric Auffray
Alexandre Boissonnas
Bruno Lucas
author_facet Aurélie Durand
Alexandra Audemard-Verger
Vincent Guichard
Raphaël Mattiuz
Arnaud Delpoux
Pauline Hamon
Nelly Bonilla
Matthieu Rivière
Jérôme Delon
Bruno Martin
Cédric Auffray
Alexandre Boissonnas
Bruno Lucas
author_sort Aurélie Durand
title Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
title_short Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
title_full Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
title_fullStr Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
title_full_unstemmed Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
title_sort profiling the lymphoid-resident t cell pool reveals modulation by age and microbiota
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6817c7ab4e8648ea9360a32bfd190459
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