Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base

Background: Cutaneous horns usually develop on a keratinocytic base with the histopathology on a spectrum ranging from benign keratosis through to invasive squamous cell carcinoma (SCC). Some features of horns are easily identified using dermatoscopy. Objective: To investigate if specific clinic...

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Autores principales:	John Pyne, Devendra Sapkota, Jian Cheng Wong
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2013
Materias:	squamous cell carcinoma cutaneous horn pain Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/681ebaf6fb7b44aaad5c9ccf9f1fbfd0
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spelling	oai:doaj.org-article:681ebaf6fb7b44aaad5c9ccf9f1fbfd02021-11-17T08:32:52ZCutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base10.5826/dpc.0302a022160-9381https://doaj.org/article/681ebaf6fb7b44aaad5c9ccf9f1fbfd02013-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/950https://doaj.org/toc/2160-9381 Background: Cutaneous horns usually develop on a keratinocytic base with the histopathology on a spectrum ranging from benign keratosis through to invasive squamous cell carcinoma (SCC). Some features of horns are easily identified using dermatoscopy. Objective: To investigate if specific clinical or dermatoscopy features of horns correlate with the histopathology in the base of the horn. Methods: Consecutive horn cases (n=163) were assessed prospectively in vivo for horn height, terrace morphology and base erythema using a Heine Delta 20 dermatoscope. Cases with potentially confounding influences were excluded. A history of horn pain or pain on palpation was also recorded. Results: Benign keratosis (n = 49), actinic keratosis (n = 21), SCC in situ (n = 37) and invasive SCC (n = 56) were recorded. An invasive SCC presenting as a horn as most likely to have a height less than the base diameter, 66% (37/56). Compared to the other study entities, invasive SCC tends to have less terrace morphology (P<0.05), a higher incidence of base erythema (P<0.05) and more pain (P<0.01). Limitations: Data categories did not include anatomic site or horn growth rates. Excision selection bias favored the incidence of invasive SCC. Conclusions: Horns presenting on an invasive SCC base are more likely to have a height less than the diameter of the base, not to have terrace morphology, to have an erythematous base and to be painful. John PyneDevendra SapkotaJian Cheng WongMattioli1885articlesquamous cell carcinomacutaneous hornpainDermatologyRL1-803ENDermatology Practical & Conceptual (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	squamous cell carcinoma cutaneous horn pain Dermatology RL1-803
spellingShingle	squamous cell carcinoma cutaneous horn pain Dermatology RL1-803 John Pyne Devendra Sapkota Jian Cheng Wong Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
description	Background: Cutaneous horns usually develop on a keratinocytic base with the histopathology on a spectrum ranging from benign keratosis through to invasive squamous cell carcinoma (SCC). Some features of horns are easily identified using dermatoscopy. Objective: To investigate if specific clinical or dermatoscopy features of horns correlate with the histopathology in the base of the horn. Methods: Consecutive horn cases (n=163) were assessed prospectively in vivo for horn height, terrace morphology and base erythema using a Heine Delta 20 dermatoscope. Cases with potentially confounding influences were excluded. A history of horn pain or pain on palpation was also recorded. Results: Benign keratosis (n = 49), actinic keratosis (n = 21), SCC in situ (n = 37) and invasive SCC (n = 56) were recorded. An invasive SCC presenting as a horn as most likely to have a height less than the base diameter, 66% (37/56). Compared to the other study entities, invasive SCC tends to have less terrace morphology (P<0.05), a higher incidence of base erythema (P<0.05) and more pain (P<0.01). Limitations: Data categories did not include anatomic site or horn growth rates. Excision selection bias favored the incidence of invasive SCC. Conclusions: Horns presenting on an invasive SCC base are more likely to have a height less than the diameter of the base, not to have terrace morphology, to have an erythematous base and to be painful.
format	article
author	John Pyne Devendra Sapkota Jian Cheng Wong
author_facet	John Pyne Devendra Sapkota Jian Cheng Wong
author_sort	John Pyne
title	Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
title_short	Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
title_full	Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
title_fullStr	Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
title_full_unstemmed	Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
title_sort	cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base
publisher	Mattioli1885
publishDate	2013
url	https://doaj.org/article/681ebaf6fb7b44aaad5c9ccf9f1fbfd0
work_keys_str_mv	AT johnpyne cutaneoushornscluestoinvasivesquamouscellcarcinomabeingpresentinthehornbase AT devendrasapkota cutaneoushornscluestoinvasivesquamouscellcarcinomabeingpresentinthehornbase AT jianchengwong cutaneoushornscluestoinvasivesquamouscellcarcinomabeingpresentinthehornbase
_version_	1718425675985059840

Cutaneous horns: clues to invasive squamous cell carcinoma being present in the horn base

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