A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells

The BAF complex is a multi-subunit chromatin remodeling complex that plays important roles in transcription regulation. Here the authors provide evidence that BRD9 and GLTSCR1/BICRA or its paralog GLTSCR1-like/BICRAL define a non-canonical BAF complex that regulates naive pluripotency in mouse embry...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jovylyn Gatchalian, Shivani Malik, Josephine Ho, Dong-Sung Lee, Timothy W. R. Kelso, Maxim N. Shokhirev, Jesse R. Dixon, Diana C. Hargreaves
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/68252e2a987241adafd12cb3fa6d9025
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:68252e2a987241adafd12cb3fa6d9025
record_format dspace
spelling oai:doaj.org-article:68252e2a987241adafd12cb3fa6d90252021-12-02T15:34:40ZA non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells10.1038/s41467-018-07528-92041-1723https://doaj.org/article/68252e2a987241adafd12cb3fa6d90252018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07528-9https://doaj.org/toc/2041-1723The BAF complex is a multi-subunit chromatin remodeling complex that plays important roles in transcription regulation. Here the authors provide evidence that BRD9 and GLTSCR1/BICRA or its paralog GLTSCR1-like/BICRAL define a non-canonical BAF complex that regulates naive pluripotency in mouse embryonic stem cells.Jovylyn GatchalianShivani MalikJosephine HoDong-Sung LeeTimothy W. R. KelsoMaxim N. ShokhirevJesse R. DixonDiana C. HargreavesNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jovylyn Gatchalian
Shivani Malik
Josephine Ho
Dong-Sung Lee
Timothy W. R. Kelso
Maxim N. Shokhirev
Jesse R. Dixon
Diana C. Hargreaves
A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
description The BAF complex is a multi-subunit chromatin remodeling complex that plays important roles in transcription regulation. Here the authors provide evidence that BRD9 and GLTSCR1/BICRA or its paralog GLTSCR1-like/BICRAL define a non-canonical BAF complex that regulates naive pluripotency in mouse embryonic stem cells.
format article
author Jovylyn Gatchalian
Shivani Malik
Josephine Ho
Dong-Sung Lee
Timothy W. R. Kelso
Maxim N. Shokhirev
Jesse R. Dixon
Diana C. Hargreaves
author_facet Jovylyn Gatchalian
Shivani Malik
Josephine Ho
Dong-Sung Lee
Timothy W. R. Kelso
Maxim N. Shokhirev
Jesse R. Dixon
Diana C. Hargreaves
author_sort Jovylyn Gatchalian
title A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
title_short A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
title_full A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
title_fullStr A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
title_full_unstemmed A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
title_sort non-canonical brd9-containing baf chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/68252e2a987241adafd12cb3fa6d9025
work_keys_str_mv AT jovylyngatchalian anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT shivanimalik anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT josephineho anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT dongsunglee anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT timothywrkelso anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT maximnshokhirev anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT jesserdixon anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT dianachargreaves anoncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT jovylyngatchalian noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT shivanimalik noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT josephineho noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT dongsunglee noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT timothywrkelso noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT maximnshokhirev noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT jesserdixon noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
AT dianachargreaves noncanonicalbrd9containingbafchromatinremodelingcomplexregulatesnaivepluripotencyinmouseembryonicstemcells
_version_ 1718386784083116032