Near-atomic resolution structures of interdigitated nucleosome fibres

Crystal structures of nucleosome fibres assembled from cohesive-ended dinucleosomes with and without linker histone reveal open zigzag conformations that are interdigitated with one another, and suggest the role that linker DNA plays in observed variable fibre configurations and packing.

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Auteurs principaux: Zenita Adhireksan, Deepti Sharma, Phoi Leng Lee, Curt A. Davey
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/682754c2893c45cbb5a23c6df1c09574
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Résumé:Crystal structures of nucleosome fibres assembled from cohesive-ended dinucleosomes with and without linker histone reveal open zigzag conformations that are interdigitated with one another, and suggest the role that linker DNA plays in observed variable fibre configurations and packing.