A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser

Abstract To examine the applicability of plasma-mediated vitreous body removal, a diode-pumped Q-switched Neodymium:YAG laser was used for a possible application in eye surgery/vitrectomy. On a total of 1500 porcine vitreous bodies, removal rates were evaluated by comparing different LaserVit-tip de...

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Autores principales:	Daniel Uthoff, Rita Oravecz, Romina Kuehnl, Friederike Rubin-Schwarz, Matthias Frentzen, Norbert Schrage, Jörg Meister
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/68319052b1ca4768ab706e77aaae3323
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spelling	oai:doaj.org-article:68319052b1ca4768ab706e77aaae33232021-12-02T12:33:15ZA promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser10.1038/s41598-020-78878-y2045-2322https://doaj.org/article/68319052b1ca4768ab706e77aaae33232020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78878-yhttps://doaj.org/toc/2045-2322Abstract To examine the applicability of plasma-mediated vitreous body removal, a diode-pumped Q-switched Neodymium:YAG laser was used for a possible application in eye surgery/vitrectomy. On a total of 1500 porcine vitreous bodies, removal rates were evaluated by comparing different LaserVit-tip designs (Mark I/II Gauge 19 and Mark III Gauge 22). The Nd:YAG laser, operating at a wavelength of 1064 nm and a pulse duration of 4 ns, was utilized for vitreous body removal with respective settings of 2, 3 and 4 mJ and pulse repetition rates (cut rates) from 5 to 25 Hz (300–1500 /min) in 5 Hz-steps as well as for 100 Hz (6000 cuts/min). The exposure times were selected at 10, 20, 40 and 60 s, respectively. Comparative measurements were carried out with mechanical cutters (Gauge 20 and Gauge 23), applying a fixed cut rate of 800 /min (13.33 Hz) at identical exposure times. The LaserVit-tips showed successful vitreous body removal for all laser settings and exposure times (Mark I: 6.2 g/min, Mark II: 8.2 g/min at 1500 cuts/min and 3 mJ, Mark II: 10.1 g/min, Mark III: 3.6 g/min at 6000 cuts/min at 3 mJ). Similar tip-dimensions (Gauge 22laser and Gauge 23cutter) showed comparable removal rates of 3.6 g/minlaser and 1.3 g/mincutter with settings of 6000 cuts/min at 3 mJ (laser) and 800 cuts/min for the mechanical cutter. A diode-pumped Q-switched Nd:YAG laser can successfully and gently remove vitreous body. The efficiency of the laser was comparable to that of mechanical cutters in terms of quantity of material removed per time unit.Daniel UthoffRita OraveczRomina KuehnlFriederike Rubin-SchwarzMatthias FrentzenNorbert SchrageJörg MeisterNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Daniel Uthoff Rita Oravecz Romina Kuehnl Friederike Rubin-Schwarz Matthias Frentzen Norbert Schrage Jörg Meister A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser
description	Abstract To examine the applicability of plasma-mediated vitreous body removal, a diode-pumped Q-switched Neodymium:YAG laser was used for a possible application in eye surgery/vitrectomy. On a total of 1500 porcine vitreous bodies, removal rates were evaluated by comparing different LaserVit-tip designs (Mark I/II Gauge 19 and Mark III Gauge 22). The Nd:YAG laser, operating at a wavelength of 1064 nm and a pulse duration of 4 ns, was utilized for vitreous body removal with respective settings of 2, 3 and 4 mJ and pulse repetition rates (cut rates) from 5 to 25 Hz (300–1500 /min) in 5 Hz-steps as well as for 100 Hz (6000 cuts/min). The exposure times were selected at 10, 20, 40 and 60 s, respectively. Comparative measurements were carried out with mechanical cutters (Gauge 20 and Gauge 23), applying a fixed cut rate of 800 /min (13.33 Hz) at identical exposure times. The LaserVit-tips showed successful vitreous body removal for all laser settings and exposure times (Mark I: 6.2 g/min, Mark II: 8.2 g/min at 1500 cuts/min and 3 mJ, Mark II: 10.1 g/min, Mark III: 3.6 g/min at 6000 cuts/min at 3 mJ). Similar tip-dimensions (Gauge 22laser and Gauge 23cutter) showed comparable removal rates of 3.6 g/minlaser and 1.3 g/mincutter with settings of 6000 cuts/min at 3 mJ (laser) and 800 cuts/min for the mechanical cutter. A diode-pumped Q-switched Nd:YAG laser can successfully and gently remove vitreous body. The efficiency of the laser was comparable to that of mechanical cutters in terms of quantity of material removed per time unit.
format	article
author	Daniel Uthoff Rita Oravecz Romina Kuehnl Friederike Rubin-Schwarz Matthias Frentzen Norbert Schrage Jörg Meister
author_facet	Daniel Uthoff Rita Oravecz Romina Kuehnl Friederike Rubin-Schwarz Matthias Frentzen Norbert Schrage Jörg Meister
author_sort	Daniel Uthoff
title	A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser
title_short	A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser
title_full	A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser
title_fullStr	A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser
title_full_unstemmed	A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser
title_sort	promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped q-switched nd:yag laser
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/68319052b1ca4768ab706e77aaae3323
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A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser

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