The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression

LncRNAs have been associated with cancer. Here, the authors carry out a systematic review of lncRNAs in breast cancer and show that DSCAM-AS1is highly expressed in oestrogen receptor positive tumours and enhances cancer through an interaction with hnRNPL; and is also associated with tamoxifen resist...

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Autores principales: Yashar S. Niknafs, Sumin Han, Teng Ma, Corey Speers, Chao Zhang, Kari Wilder-Romans, Matthew K. Iyer, Sethuramasundaram Pitchiaya, Rohit Malik, Yasuyuki Hosono, John R. Prensner, Anton Poliakov, Udit Singhal, Lanbo Xiao, Steven Kregel, Ronald F. Siebenaler, Shuang G. Zhao, Michael Uhl, Alexander Gawronski, Daniel F. Hayes, Lori J. Pierce, Xuhong Cao, Colin Collins, Rolf Backofen, Cenk S. Sahinalp, James M. Rae, Arul M. Chinnaiyan, Felix Y. Feng
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/683cca27103c413a96704a7bec3d8d79
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spelling oai:doaj.org-article:683cca27103c413a96704a7bec3d8d792021-12-02T15:33:48ZThe lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression10.1038/ncomms127912041-1723https://doaj.org/article/683cca27103c413a96704a7bec3d8d792016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12791https://doaj.org/toc/2041-1723LncRNAs have been associated with cancer. Here, the authors carry out a systematic review of lncRNAs in breast cancer and show that DSCAM-AS1is highly expressed in oestrogen receptor positive tumours and enhances cancer through an interaction with hnRNPL; and is also associated with tamoxifen resistance.Yashar S. NiknafsSumin HanTeng MaCorey SpeersChao ZhangKari Wilder-RomansMatthew K. IyerSethuramasundaram PitchiayaRohit MalikYasuyuki HosonoJohn R. PrensnerAnton PoliakovUdit SinghalLanbo XiaoSteven KregelRonald F. SiebenalerShuang G. ZhaoMichael UhlAlexander GawronskiDaniel F. HayesLori J. PierceXuhong CaoColin CollinsRolf BackofenCenk S. SahinalpJames M. RaeArul M. ChinnaiyanFelix Y. FengNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yashar S. Niknafs
Sumin Han
Teng Ma
Corey Speers
Chao Zhang
Kari Wilder-Romans
Matthew K. Iyer
Sethuramasundaram Pitchiaya
Rohit Malik
Yasuyuki Hosono
John R. Prensner
Anton Poliakov
Udit Singhal
Lanbo Xiao
Steven Kregel
Ronald F. Siebenaler
Shuang G. Zhao
Michael Uhl
Alexander Gawronski
Daniel F. Hayes
Lori J. Pierce
Xuhong Cao
Colin Collins
Rolf Backofen
Cenk S. Sahinalp
James M. Rae
Arul M. Chinnaiyan
Felix Y. Feng
The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
description LncRNAs have been associated with cancer. Here, the authors carry out a systematic review of lncRNAs in breast cancer and show that DSCAM-AS1is highly expressed in oestrogen receptor positive tumours and enhances cancer through an interaction with hnRNPL; and is also associated with tamoxifen resistance.
format article
author Yashar S. Niknafs
Sumin Han
Teng Ma
Corey Speers
Chao Zhang
Kari Wilder-Romans
Matthew K. Iyer
Sethuramasundaram Pitchiaya
Rohit Malik
Yasuyuki Hosono
John R. Prensner
Anton Poliakov
Udit Singhal
Lanbo Xiao
Steven Kregel
Ronald F. Siebenaler
Shuang G. Zhao
Michael Uhl
Alexander Gawronski
Daniel F. Hayes
Lori J. Pierce
Xuhong Cao
Colin Collins
Rolf Backofen
Cenk S. Sahinalp
James M. Rae
Arul M. Chinnaiyan
Felix Y. Feng
author_facet Yashar S. Niknafs
Sumin Han
Teng Ma
Corey Speers
Chao Zhang
Kari Wilder-Romans
Matthew K. Iyer
Sethuramasundaram Pitchiaya
Rohit Malik
Yasuyuki Hosono
John R. Prensner
Anton Poliakov
Udit Singhal
Lanbo Xiao
Steven Kregel
Ronald F. Siebenaler
Shuang G. Zhao
Michael Uhl
Alexander Gawronski
Daniel F. Hayes
Lori J. Pierce
Xuhong Cao
Colin Collins
Rolf Backofen
Cenk S. Sahinalp
James M. Rae
Arul M. Chinnaiyan
Felix Y. Feng
author_sort Yashar S. Niknafs
title The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
title_short The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
title_full The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
title_fullStr The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
title_full_unstemmed The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
title_sort lncrna landscape of breast cancer reveals a role for dscam-as1 in breast cancer progression
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/683cca27103c413a96704a7bec3d8d79
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