Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells.

Vascular calcification, which results from a process osteoblastic differentiation of vascular smooth muscle cells (VSMCs), is a major risk factor for cardiovascular morbidity and mortality. Apelin is a recently discovered peptide that is the endogenous ligand for the orphan G-protein-coupled recepto...

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Autores principales: Peng-Fei Shan, Ying Lu, Rong-Rong Cui, Yi Jiang, Ling-Qing Yuan, Er-Yuan Liao
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/68493a50a4a348c38739a65ef50dbd00
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