mSphere of Influence: Experimental Evolution of RNA Viruses

ABSTRACT Gonzalo Moratorio works in the field of experimental evolution of viruses. In this mSphere of Influence article, he reflects on how the papers “Virus attenuation by genome-scale changes in codon pair bias” by Coleman et al. (Science 320:1784–1787, 2008, https://doi.org/10.1126/science.11557...

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Autor principal:	Gonzalo Moratorio
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	virus attenuation synthetic biology codon pair bias mutational robustness Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/684a60d0eedf456196042b1db6702306
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spelling	oai:doaj.org-article:684a60d0eedf456196042b1db67023062021-11-15T15:29:17ZmSphere of Influence: Experimental Evolution of RNA Viruses10.1128/mSphere.00179-202379-5042https://doaj.org/article/684a60d0eedf456196042b1db67023062020-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00179-20https://doaj.org/toc/2379-5042ABSTRACT Gonzalo Moratorio works in the field of experimental evolution of viruses. In this mSphere of Influence article, he reflects on how the papers “Virus attenuation by genome-scale changes in codon pair bias” by Coleman et al. (Science 320:1784–1787, 2008, https://doi.org/10.1126/science.1155761) and “Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus” by Lauring et al. (Cell Host Microbe 12:623–632, 2012, https://doi.org/10.1016/j.chom.2012.10.008) made an impact on his thinking about how to employ synthetic biology to study experimental evolution of viruses.Gonzalo MoratorioAmerican Society for Microbiologyarticlevirus attenuationsynthetic biologycodon pair biasmutational robustnessMicrobiologyQR1-502ENmSphere, Vol 5, Iss 2 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	virus attenuation synthetic biology codon pair bias mutational robustness Microbiology QR1-502
spellingShingle	virus attenuation synthetic biology codon pair bias mutational robustness Microbiology QR1-502 Gonzalo Moratorio mSphere of Influence: Experimental Evolution of RNA Viruses
description	ABSTRACT Gonzalo Moratorio works in the field of experimental evolution of viruses. In this mSphere of Influence article, he reflects on how the papers “Virus attenuation by genome-scale changes in codon pair bias” by Coleman et al. (Science 320:1784–1787, 2008, https://doi.org/10.1126/science.1155761) and “Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus” by Lauring et al. (Cell Host Microbe 12:623–632, 2012, https://doi.org/10.1016/j.chom.2012.10.008) made an impact on his thinking about how to employ synthetic biology to study experimental evolution of viruses.
format	article
author	Gonzalo Moratorio
author_facet	Gonzalo Moratorio
author_sort	Gonzalo Moratorio
title	mSphere of Influence: Experimental Evolution of RNA Viruses
title_short	mSphere of Influence: Experimental Evolution of RNA Viruses
title_full	mSphere of Influence: Experimental Evolution of RNA Viruses
title_fullStr	mSphere of Influence: Experimental Evolution of RNA Viruses
title_full_unstemmed	mSphere of Influence: Experimental Evolution of RNA Viruses
title_sort	msphere of influence: experimental evolution of rna viruses
publisher	American Society for Microbiology
publishDate	2020
url	https://doaj.org/article/684a60d0eedf456196042b1db6702306
work_keys_str_mv	AT gonzalomoratorio msphereofinfluenceexperimentalevolutionofrnaviruses
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mSphere of Influence: Experimental Evolution of RNA Viruses

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