Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance

Abstract Surfaces with hydrophilic and antimicrobial properties are very attractive for cardiovascular device‐associated applications. The aim of this study was to prepare and coat a hydrophilic polymer containing a functional group capable of forming triazole functionality onto the surface of polyu...

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Autores principales:	Xin Wen, Rashed Almousa, Sungsoo Na, Gregory G. Anderson, Dong Xie
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	bacterial adhesion and inhibition cell adhesion polymer coating polyurethane Biotechnology TP248.13-248.65 Biochemistry QD415-436
Acceso en línea:	https://doaj.org/article/684e514c36ab456eb007b66e306be453
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spelling	oai:doaj.org-article:684e514c36ab456eb007b66e306be4532021-11-12T15:58:04ZPolyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance2405-451810.1049/bsb2.12023https://doaj.org/article/684e514c36ab456eb007b66e306be4532021-12-01T00:00:00Zhttps://doi.org/10.1049/bsb2.12023https://doaj.org/toc/2405-4518Abstract Surfaces with hydrophilic and antimicrobial properties are very attractive for cardiovascular device‐associated applications. The aim of this study was to prepare and coat a hydrophilic polymer containing a functional group capable of forming triazole functionality onto the surface of polyurethane (PU). The modified surfaces were assessed with cell adhesion, bacterial adhesion and bacterial viability. Mouse fibroblast cells (NIH‐3T3) and three bacterial species were used for assessment. The results showed that the modified surface not only exhibited a significant reduction in cell adhesion with a 25%–59% decrease to mouse fibroblast but also showed a significant reduction in bacterial attachment with 26%–67%, 24%–61% and 23%–57% decrease to Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, respectively, as compared with original PU. Furthermore, the polymer‐modified surface exhibited a significant antibacterial function by inhibiting bacterial growth with reduction of 49%–84%, 44%–79% and 53%–79% to S. aureus, E. coli and P. aeruginosa, respectively, as compared with original PU. These results indicate that covalent polymer attachment enhanced the antibacterial and antifouling properties of the PU surface.Xin WenRashed AlmousaSungsoo NaGregory G. AndersonDong XieWileyarticlebacterial adhesion and inhibitioncell adhesionpolymer coatingpolyurethaneBiotechnologyTP248.13-248.65BiochemistryQD415-436ENBiosurface and Biotribology, Vol 7, Iss 4, Pp 219-227 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bacterial adhesion and inhibition cell adhesion polymer coating polyurethane Biotechnology TP248.13-248.65 Biochemistry QD415-436
spellingShingle	bacterial adhesion and inhibition cell adhesion polymer coating polyurethane Biotechnology TP248.13-248.65 Biochemistry QD415-436 Xin Wen Rashed Almousa Sungsoo Na Gregory G. Anderson Dong Xie Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
description	Abstract Surfaces with hydrophilic and antimicrobial properties are very attractive for cardiovascular device‐associated applications. The aim of this study was to prepare and coat a hydrophilic polymer containing a functional group capable of forming triazole functionality onto the surface of polyurethane (PU). The modified surfaces were assessed with cell adhesion, bacterial adhesion and bacterial viability. Mouse fibroblast cells (NIH‐3T3) and three bacterial species were used for assessment. The results showed that the modified surface not only exhibited a significant reduction in cell adhesion with a 25%–59% decrease to mouse fibroblast but also showed a significant reduction in bacterial attachment with 26%–67%, 24%–61% and 23%–57% decrease to Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, respectively, as compared with original PU. Furthermore, the polymer‐modified surface exhibited a significant antibacterial function by inhibiting bacterial growth with reduction of 49%–84%, 44%–79% and 53%–79% to S. aureus, E. coli and P. aeruginosa, respectively, as compared with original PU. These results indicate that covalent polymer attachment enhanced the antibacterial and antifouling properties of the PU surface.
format	article
author	Xin Wen Rashed Almousa Sungsoo Na Gregory G. Anderson Dong Xie
author_facet	Xin Wen Rashed Almousa Sungsoo Na Gregory G. Anderson Dong Xie
author_sort	Xin Wen
title	Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
title_short	Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
title_full	Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
title_fullStr	Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
title_full_unstemmed	Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
title_sort	polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/684e514c36ab456eb007b66e306be453
work_keys_str_mv	AT xinwen polyurethanecoatedwithpolyvinylpyrrolidonesviatriazolelinksforenhancedsurfacefoulingresistance AT rashedalmousa polyurethanecoatedwithpolyvinylpyrrolidonesviatriazolelinksforenhancedsurfacefoulingresistance AT sungsoona polyurethanecoatedwithpolyvinylpyrrolidonesviatriazolelinksforenhancedsurfacefoulingresistance AT gregoryganderson polyurethanecoatedwithpolyvinylpyrrolidonesviatriazolelinksforenhancedsurfacefoulingresistance AT dongxie polyurethanecoatedwithpolyvinylpyrrolidonesviatriazolelinksforenhancedsurfacefoulingresistance
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Polyurethane coated with polyvinylpyrrolidones via triazole links for enhanced surface fouling resistance

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