Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy

Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows studying MAP-MT interactions.

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Autores principales:	Yanzhang Luo, ShengQi Xiang, Peter Jan Hooikaas, Laura van Bezouwen, A. S. Jijumon, Carsten Janke, Friedrich Förster, Anna Akhmanova, Marc Baldus
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6857f9ffb0814bc9a9cc46cdf3ff87e4
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spelling	oai:doaj.org-article:6857f9ffb0814bc9a9cc46cdf3ff87e42021-12-02T15:34:34ZDirect observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy10.1038/s41467-019-13876-x2041-1723https://doaj.org/article/6857f9ffb0814bc9a9cc46cdf3ff87e42020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13876-xhttps://doaj.org/toc/2041-1723Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows studying MAP-MT interactions.Yanzhang LuoShengQi XiangPeter Jan HooikaasLaura van BezouwenA. S. JijumonCarsten JankeFriedrich FörsterAnna AkhmanovaMarc BaldusNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yanzhang Luo ShengQi Xiang Peter Jan Hooikaas Laura van Bezouwen A. S. Jijumon Carsten Janke Friedrich Förster Anna Akhmanova Marc Baldus Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
description	Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows studying MAP-MT interactions.
format	article
author	Yanzhang Luo ShengQi Xiang Peter Jan Hooikaas Laura van Bezouwen A. S. Jijumon Carsten Janke Friedrich Förster Anna Akhmanova Marc Baldus
author_facet	Yanzhang Luo ShengQi Xiang Peter Jan Hooikaas Laura van Bezouwen A. S. Jijumon Carsten Janke Friedrich Förster Anna Akhmanova Marc Baldus
author_sort	Yanzhang Luo
title	Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
title_short	Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
title_full	Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
title_fullStr	Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
title_full_unstemmed	Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy
title_sort	direct observation of dynamic protein interactions involving human microtubules using solid-state nmr spectroscopy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6857f9ffb0814bc9a9cc46cdf3ff87e4
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Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy

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