Serine/Threonine Protein Phosphatase-Mediated Control of the Peptidoglycan Cross-Linking <sc>l</sc>,<sc>d</sc><sc>-</sc>Transpeptidase Pathway in <named-content content-type="genus-species">Enterococcus faecium</named-content>
ABSTRACT The last step of peptidoglycan polymerization involves two families of unrelated transpeptidases that are the essential targets of β-lactam antibiotics. d,d-transpeptidases of the penicillin-binding protein (PBP) family are active-site serine enzymes that use pentapeptide precursors and are...
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Main Authors: | Emmanuelle Sacco, Mélanie Cortes, Nathalie Josseaume, Louis B. Rice, Jean-Luc Mainardi, Michel Arthur |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2014
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Online Access: | https://doaj.org/article/6859b98ddb5544f7ae118d19c4ba878a |
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