Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study
Abstract Background This study assessed the impact of the COVID-19 epidemic on overall hospitalizations for pulmonary embolism (PE) in France in comparison with previous years, and by COVID-19 and non-COVID-19 status. Methods Hospitalization data (2017–2020) were extracted from the French National D...
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
BMC
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/685f05cc75434d5892787ded40d4176f |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:685f05cc75434d5892787ded40d4176f |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:685f05cc75434d5892787ded40d4176f2021-11-21T12:32:00ZImpact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study10.1186/s12931-021-01887-61465-993Xhttps://doaj.org/article/685f05cc75434d5892787ded40d4176f2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12931-021-01887-6https://doaj.org/toc/1465-993XAbstract Background This study assessed the impact of the COVID-19 epidemic on overall hospitalizations for pulmonary embolism (PE) in France in comparison with previous years, and by COVID-19 and non-COVID-19 status. Methods Hospitalization data (2017–2020) were extracted from the French National Discharge database (all public and private hospitals). We included all patients older than 18 years hospitalized during the 3 years and extracted PE status and COVID-19 status (from March 2020). Age, sex and risk factors for PE (such as obesity, cancer) were identified. We also extracted transfer to an intensive care unit (ICU) and hospital death. The number of PE and the frequency of death in patients in 2019 and 2020 were described by month and by COVID-19 status. Logistic regressions were performed to identify the role of COVID-19 among other risk factors for PE in hospitalized patients. Results The overall number of patients hospitalized with PE increased by about 16% in 2020 compared with 2019, and mortality also increased to 10.3% (+ 1.2%). These increases were mostly linked to COVID-19 waves, which were associated with PE hospitalization in COVID-19 patients (PE frequency was 3.7%; 2.8% in non-ICU and 8.8% in ICU). The final PE odds ratio for COVID-19 hospitalized patients was 4 compared with other hospitalized patients in 2020. The analyses of PE in non-COVID-19 patients showed a 2.7% increase in 2020 compared with the previous three years. Conclusion In 2020, the overall number of patients hospitalized with PE in France increased compared to the previous three years despite a considerable decrease in scheduled hospitalizations. Nevertheless, proactive public policy focused on the prevention of PE in all patients should be encouraged.Pierre TankereJonathan CottenetPascale Tubert-BitterAnne-Sophie MarietGuillaume BeltramoJacques CadranelLionel PirothPhilippe BonniaudCatherine QuantinBMCarticleCOVID-19Pulmonary embolismMedico-administrative dataHospitalLockdownSARS-COV2Diseases of the respiratory systemRC705-779ENRespiratory Research, Vol 22, Iss 1, Pp 1-11 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
COVID-19 Pulmonary embolism Medico-administrative data Hospital Lockdown SARS-COV2 Diseases of the respiratory system RC705-779 |
| spellingShingle |
COVID-19 Pulmonary embolism Medico-administrative data Hospital Lockdown SARS-COV2 Diseases of the respiratory system RC705-779 Pierre Tankere Jonathan Cottenet Pascale Tubert-Bitter Anne-Sophie Mariet Guillaume Beltramo Jacques Cadranel Lionel Piroth Philippe Bonniaud Catherine Quantin Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study |
| description |
Abstract Background This study assessed the impact of the COVID-19 epidemic on overall hospitalizations for pulmonary embolism (PE) in France in comparison with previous years, and by COVID-19 and non-COVID-19 status. Methods Hospitalization data (2017–2020) were extracted from the French National Discharge database (all public and private hospitals). We included all patients older than 18 years hospitalized during the 3 years and extracted PE status and COVID-19 status (from March 2020). Age, sex and risk factors for PE (such as obesity, cancer) were identified. We also extracted transfer to an intensive care unit (ICU) and hospital death. The number of PE and the frequency of death in patients in 2019 and 2020 were described by month and by COVID-19 status. Logistic regressions were performed to identify the role of COVID-19 among other risk factors for PE in hospitalized patients. Results The overall number of patients hospitalized with PE increased by about 16% in 2020 compared with 2019, and mortality also increased to 10.3% (+ 1.2%). These increases were mostly linked to COVID-19 waves, which were associated with PE hospitalization in COVID-19 patients (PE frequency was 3.7%; 2.8% in non-ICU and 8.8% in ICU). The final PE odds ratio for COVID-19 hospitalized patients was 4 compared with other hospitalized patients in 2020. The analyses of PE in non-COVID-19 patients showed a 2.7% increase in 2020 compared with the previous three years. Conclusion In 2020, the overall number of patients hospitalized with PE in France increased compared to the previous three years despite a considerable decrease in scheduled hospitalizations. Nevertheless, proactive public policy focused on the prevention of PE in all patients should be encouraged. |
| format |
article |
| author |
Pierre Tankere Jonathan Cottenet Pascale Tubert-Bitter Anne-Sophie Mariet Guillaume Beltramo Jacques Cadranel Lionel Piroth Philippe Bonniaud Catherine Quantin |
| author_facet |
Pierre Tankere Jonathan Cottenet Pascale Tubert-Bitter Anne-Sophie Mariet Guillaume Beltramo Jacques Cadranel Lionel Piroth Philippe Bonniaud Catherine Quantin |
| author_sort |
Pierre Tankere |
| title |
Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study |
| title_short |
Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study |
| title_full |
Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study |
| title_fullStr |
Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study |
| title_full_unstemmed |
Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study |
| title_sort |
impact of covid-19 and lockdowns on pulmonary embolism in hospitalized patients in france: a nationwide study |
| publisher |
BMC |
| publishDate |
2021 |
| url |
https://doaj.org/article/685f05cc75434d5892787ded40d4176f |
| work_keys_str_mv |
AT pierretankere impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT jonathancottenet impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT pascaletubertbitter impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT annesophiemariet impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT guillaumebeltramo impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT jacquescadranel impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT lionelpiroth impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT philippebonniaud impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy AT catherinequantin impactofcovid19andlockdownsonpulmonaryembolisminhospitalizedpatientsinfranceanationwidestudy |
| _version_ |
1718418948845731840 |