Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week

The lengthy time in establishing patient-derived organoids(PDOs) hampers the implementation of PDO-based drug sensitivity tests in clinics. Here, the authors show a microwell array-based method to predict patient’s responses to anti-cancer therapies in a week using lung cancer organoids.

Guardado en:
Detalles Bibliográficos
Autores principales: Yawei Hu, Xizhao Sui, Fan Song, Yaqian Li, Kaiyi Li, Zhongyao Chen, Fan Yang, Xiuyuan Chen, Yaohua Zhang, Xianning Wang, Qiang Liu, Cong Li, Binbin Zou, Xiaofang Chen, Jun Wang, Peng Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/685fcfdd32cb48a39c362d85bdccac14
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:685fcfdd32cb48a39c362d85bdccac14
record_format dspace
spelling oai:doaj.org-article:685fcfdd32cb48a39c362d85bdccac142021-12-02T14:35:38ZLung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week10.1038/s41467-021-22676-12041-1723https://doaj.org/article/685fcfdd32cb48a39c362d85bdccac142021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22676-1https://doaj.org/toc/2041-1723The lengthy time in establishing patient-derived organoids(PDOs) hampers the implementation of PDO-based drug sensitivity tests in clinics. Here, the authors show a microwell array-based method to predict patient’s responses to anti-cancer therapies in a week using lung cancer organoids.Yawei HuXizhao SuiFan SongYaqian LiKaiyi LiZhongyao ChenFan YangXiuyuan ChenYaohua ZhangXianning WangQiang LiuCong LiBinbin ZouXiaofang ChenJun WangPeng LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yawei Hu
Xizhao Sui
Fan Song
Yaqian Li
Kaiyi Li
Zhongyao Chen
Fan Yang
Xiuyuan Chen
Yaohua Zhang
Xianning Wang
Qiang Liu
Cong Li
Binbin Zou
Xiaofang Chen
Jun Wang
Peng Liu
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
description The lengthy time in establishing patient-derived organoids(PDOs) hampers the implementation of PDO-based drug sensitivity tests in clinics. Here, the authors show a microwell array-based method to predict patient’s responses to anti-cancer therapies in a week using lung cancer organoids.
format article
author Yawei Hu
Xizhao Sui
Fan Song
Yaqian Li
Kaiyi Li
Zhongyao Chen
Fan Yang
Xiuyuan Chen
Yaohua Zhang
Xianning Wang
Qiang Liu
Cong Li
Binbin Zou
Xiaofang Chen
Jun Wang
Peng Liu
author_facet Yawei Hu
Xizhao Sui
Fan Song
Yaqian Li
Kaiyi Li
Zhongyao Chen
Fan Yang
Xiuyuan Chen
Yaohua Zhang
Xianning Wang
Qiang Liu
Cong Li
Binbin Zou
Xiaofang Chen
Jun Wang
Peng Liu
author_sort Yawei Hu
title Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
title_short Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
title_full Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
title_fullStr Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
title_full_unstemmed Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
title_sort lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/685fcfdd32cb48a39c362d85bdccac14
work_keys_str_mv AT yaweihu lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT xizhaosui lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT fansong lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT yaqianli lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT kaiyili lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT zhongyaochen lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT fanyang lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT xiuyuanchen lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT yaohuazhang lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT xianningwang lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT qiangliu lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT congli lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT binbinzou lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT xiaofangchen lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT junwang lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
AT pengliu lungcancerorganoidsanalyzedonmicrowellarrayspredictdrugresponsesofpatientswithinaweek
_version_ 1718391077428264960