Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week
The lengthy time in establishing patient-derived organoids(PDOs) hampers the implementation of PDO-based drug sensitivity tests in clinics. Here, the authors show a microwell array-based method to predict patient’s responses to anti-cancer therapies in a week using lung cancer organoids.
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Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/685fcfdd32cb48a39c362d85bdccac14 |
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oai:doaj.org-article:685fcfdd32cb48a39c362d85bdccac142021-12-02T14:35:38ZLung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week10.1038/s41467-021-22676-12041-1723https://doaj.org/article/685fcfdd32cb48a39c362d85bdccac142021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22676-1https://doaj.org/toc/2041-1723The lengthy time in establishing patient-derived organoids(PDOs) hampers the implementation of PDO-based drug sensitivity tests in clinics. Here, the authors show a microwell array-based method to predict patient’s responses to anti-cancer therapies in a week using lung cancer organoids.Yawei HuXizhao SuiFan SongYaqian LiKaiyi LiZhongyao ChenFan YangXiuyuan ChenYaohua ZhangXianning WangQiang LiuCong LiBinbin ZouXiaofang ChenJun WangPeng LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Yawei Hu Xizhao Sui Fan Song Yaqian Li Kaiyi Li Zhongyao Chen Fan Yang Xiuyuan Chen Yaohua Zhang Xianning Wang Qiang Liu Cong Li Binbin Zou Xiaofang Chen Jun Wang Peng Liu Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
description |
The lengthy time in establishing patient-derived organoids(PDOs) hampers the implementation of PDO-based drug sensitivity tests in clinics. Here, the authors show a microwell array-based method to predict patient’s responses to anti-cancer therapies in a week using lung cancer organoids. |
format |
article |
author |
Yawei Hu Xizhao Sui Fan Song Yaqian Li Kaiyi Li Zhongyao Chen Fan Yang Xiuyuan Chen Yaohua Zhang Xianning Wang Qiang Liu Cong Li Binbin Zou Xiaofang Chen Jun Wang Peng Liu |
author_facet |
Yawei Hu Xizhao Sui Fan Song Yaqian Li Kaiyi Li Zhongyao Chen Fan Yang Xiuyuan Chen Yaohua Zhang Xianning Wang Qiang Liu Cong Li Binbin Zou Xiaofang Chen Jun Wang Peng Liu |
author_sort |
Yawei Hu |
title |
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
title_short |
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
title_full |
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
title_fullStr |
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
title_full_unstemmed |
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
title_sort |
lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/685fcfdd32cb48a39c362d85bdccac14 |
work_keys_str_mv |
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