Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions
Endomucin is expressed by endothelial cells that line postcapillary venules—the site of leukocyte recruitment during inflammation. Zahr et al.show that endomucin is an anti-adhesive molecule that is downregulated by the cytokine TNF-a and thereby helps in the transition from a quiescent to a pro-adh...
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Nature Portfolio
2016
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oai:doaj.org-article:6861100b28e4491db16608726f0aa7d82021-12-02T15:33:50ZEndomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions10.1038/ncomms103632041-1723https://doaj.org/article/6861100b28e4491db16608726f0aa7d82016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10363https://doaj.org/toc/2041-1723Endomucin is expressed by endothelial cells that line postcapillary venules—the site of leukocyte recruitment during inflammation. Zahr et al.show that endomucin is an anti-adhesive molecule that is downregulated by the cytokine TNF-a and thereby helps in the transition from a quiescent to a pro-adhesive inflamed endothelium.Alisar ZahrPilar AlcaideJinling YangAlexander JonesMeredith GregoryNathaniel G. dela PazSunita Patel-HettTania NeversAdarsha KoiralaFrancis W. LuscinskasMagali Saint-GeniezBruce KsanderPatricia A. D’AmorePablo ArgüesoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Alisar Zahr Pilar Alcaide Jinling Yang Alexander Jones Meredith Gregory Nathaniel G. dela Paz Sunita Patel-Hett Tania Nevers Adarsha Koirala Francis W. Luscinskas Magali Saint-Geniez Bruce Ksander Patricia A. D’Amore Pablo Argüeso Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| description |
Endomucin is expressed by endothelial cells that line postcapillary venules—the site of leukocyte recruitment during inflammation. Zahr et al.show that endomucin is an anti-adhesive molecule that is downregulated by the cytokine TNF-a and thereby helps in the transition from a quiescent to a pro-adhesive inflamed endothelium. |
| format |
article |
| author |
Alisar Zahr Pilar Alcaide Jinling Yang Alexander Jones Meredith Gregory Nathaniel G. dela Paz Sunita Patel-Hett Tania Nevers Adarsha Koirala Francis W. Luscinskas Magali Saint-Geniez Bruce Ksander Patricia A. D’Amore Pablo Argüeso |
| author_facet |
Alisar Zahr Pilar Alcaide Jinling Yang Alexander Jones Meredith Gregory Nathaniel G. dela Paz Sunita Patel-Hett Tania Nevers Adarsha Koirala Francis W. Luscinskas Magali Saint-Geniez Bruce Ksander Patricia A. D’Amore Pablo Argüeso |
| author_sort |
Alisar Zahr |
| title |
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| title_short |
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| title_full |
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| title_fullStr |
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| title_full_unstemmed |
Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| title_sort |
endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/6861100b28e4491db16608726f0aa7d8 |
| work_keys_str_mv |
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