Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions

Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions

Endomucin is expressed by endothelial cells that line postcapillary venules—the site of leukocyte recruitment during inflammation. Zahr et al.show that endomucin is an anti-adhesive molecule that is downregulated by the cytokine TNF-a and thereby helps in the transition from a quiescent to a pro-adh...

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Autores principales: Alisar Zahr, Pilar Alcaide, Jinling Yang, Alexander Jones, Meredith Gregory, Nathaniel G. dela Paz, Sunita Patel-Hett, Tania Nevers, Adarsha Koirala, Francis W. Luscinskas, Magali Saint-Geniez, Bruce Ksander, Patricia A. D’Amore, Pablo Argüeso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/6861100b28e4491db16608726f0aa7d8
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