BEX1 is an RNA-dependent mediator of cardiomyopathy

Little is known about the changes in mRNA splicing, processing and stability that can alter gene expression during heart failure. Here, the authors show that BEX1 is induced during heart failure and is part of a ribonucleoprotein complex enhancing the expression and stability of proinflammatory gene...

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Autores principales:	Federica Accornero, Tobias G. Schips, Jennifer M. Petrosino, Shan-Qing Gu, Onur Kanisicak, Jop H. van Berlo, Jeffery D. Molkentin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6869b96703654f77bdb47ffe9c5e9636
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spelling	oai:doaj.org-article:6869b96703654f77bdb47ffe9c5e96362021-12-02T14:40:49ZBEX1 is an RNA-dependent mediator of cardiomyopathy10.1038/s41467-017-02005-12041-1723https://doaj.org/article/6869b96703654f77bdb47ffe9c5e96362017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02005-1https://doaj.org/toc/2041-1723Little is known about the changes in mRNA splicing, processing and stability that can alter gene expression during heart failure. Here, the authors show that BEX1 is induced during heart failure and is part of a ribonucleoprotein complex enhancing the expression and stability of proinflammatory genes.Federica AccorneroTobias G. SchipsJennifer M. PetrosinoShan-Qing GuOnur KanisicakJop H. van BerloJeffery D. MolkentinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Federica Accornero Tobias G. Schips Jennifer M. Petrosino Shan-Qing Gu Onur Kanisicak Jop H. van Berlo Jeffery D. Molkentin BEX1 is an RNA-dependent mediator of cardiomyopathy
description	Little is known about the changes in mRNA splicing, processing and stability that can alter gene expression during heart failure. Here, the authors show that BEX1 is induced during heart failure and is part of a ribonucleoprotein complex enhancing the expression and stability of proinflammatory genes.
format	article
author	Federica Accornero Tobias G. Schips Jennifer M. Petrosino Shan-Qing Gu Onur Kanisicak Jop H. van Berlo Jeffery D. Molkentin
author_facet	Federica Accornero Tobias G. Schips Jennifer M. Petrosino Shan-Qing Gu Onur Kanisicak Jop H. van Berlo Jeffery D. Molkentin
author_sort	Federica Accornero
title	BEX1 is an RNA-dependent mediator of cardiomyopathy
title_short	BEX1 is an RNA-dependent mediator of cardiomyopathy
title_full	BEX1 is an RNA-dependent mediator of cardiomyopathy
title_fullStr	BEX1 is an RNA-dependent mediator of cardiomyopathy
title_full_unstemmed	BEX1 is an RNA-dependent mediator of cardiomyopathy
title_sort	bex1 is an rna-dependent mediator of cardiomyopathy
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6869b96703654f77bdb47ffe9c5e9636
work_keys_str_mv	AT federicaaccornero bex1isanrnadependentmediatorofcardiomyopathy AT tobiasgschips bex1isanrnadependentmediatorofcardiomyopathy AT jennifermpetrosino bex1isanrnadependentmediatorofcardiomyopathy AT shanqinggu bex1isanrnadependentmediatorofcardiomyopathy AT onurkanisicak bex1isanrnadependentmediatorofcardiomyopathy AT jophvanberlo bex1isanrnadependentmediatorofcardiomyopathy AT jefferydmolkentin bex1isanrnadependentmediatorofcardiomyopathy
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BEX1 is an RNA-dependent mediator of cardiomyopathy

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