Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression
Cdc48/p97 is a key component of the ubiquitin-proteasome system, acting as a ubiquitin-directed segregase to regulate multiple cellular functions. Here the authors identify UBXN-3/FAF1 as a crucial regulator of chromatin-associated protein degradation that recruits Cdc48/p97 to DNA replication forks...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/686b5c06127b4ab8a306f8fad9fed186 |
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