Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

As an interface between maternal and fetal tissues, decidua hosts immune cells specialized in fostering a successful pregnancy. Here the authors carry out high-dimensional characterization of function, morphology and surface markers of human decidual innate lymphoid cells (ILCs), identifying subsets...

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Autores principales: Oisín Huhn, Martin A. Ivarsson, Lucy Gardner, Mike Hollinshead, Jane C Stinchcombe, Puran Chen, Norman Shreeve, Olympe Chazara, Lydia E. Farrell, Jakob Theorell, Hormas Ghadially, Peter Parham, Gillian Griffiths, Amir Horowitz, Ashley Moffett, Andrew M. Sharkey, Francesco Colucci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/686fd2691411467caa9337f1f7add0f8
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Sumario:As an interface between maternal and fetal tissues, decidua hosts immune cells specialized in fostering a successful pregnancy. Here the authors carry out high-dimensional characterization of function, morphology and surface markers of human decidual innate lymphoid cells (ILCs), identifying subsets with features distinct from blood ILC.

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