Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

As an interface between maternal and fetal tissues, decidua hosts immune cells specialized in fostering a successful pregnancy. Here the authors carry out high-dimensional characterization of function, morphology and surface markers of human decidual innate lymphoid cells (ILCs), identifying subsets...

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Autores principales: Oisín Huhn, Martin A. Ivarsson, Lucy Gardner, Mike Hollinshead, Jane C Stinchcombe, Puran Chen, Norman Shreeve, Olympe Chazara, Lydia E. Farrell, Jakob Theorell, Hormas Ghadially, Peter Parham, Gillian Griffiths, Amir Horowitz, Ashley Moffett, Andrew M. Sharkey, Francesco Colucci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/686fd2691411467caa9337f1f7add0f8
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spelling oai:doaj.org-article:686fd2691411467caa9337f1f7add0f82021-12-02T14:41:24ZDistinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy10.1038/s41467-019-14123-z2041-1723https://doaj.org/article/686fd2691411467caa9337f1f7add0f82020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14123-zhttps://doaj.org/toc/2041-1723As an interface between maternal and fetal tissues, decidua hosts immune cells specialized in fostering a successful pregnancy. Here the authors carry out high-dimensional characterization of function, morphology and surface markers of human decidual innate lymphoid cells (ILCs), identifying subsets with features distinct from blood ILC.Oisín HuhnMartin A. IvarssonLucy GardnerMike HollinsheadJane C StinchcombePuran ChenNorman ShreeveOlympe ChazaraLydia E. FarrellJakob TheorellHormas GhadiallyPeter ParhamGillian GriffithsAmir HorowitzAshley MoffettAndrew M. SharkeyFrancesco ColucciNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Oisín Huhn
Martin A. Ivarsson
Lucy Gardner
Mike Hollinshead
Jane C Stinchcombe
Puran Chen
Norman Shreeve
Olympe Chazara
Lydia E. Farrell
Jakob Theorell
Hormas Ghadially
Peter Parham
Gillian Griffiths
Amir Horowitz
Ashley Moffett
Andrew M. Sharkey
Francesco Colucci
Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
description As an interface between maternal and fetal tissues, decidua hosts immune cells specialized in fostering a successful pregnancy. Here the authors carry out high-dimensional characterization of function, morphology and surface markers of human decidual innate lymphoid cells (ILCs), identifying subsets with features distinct from blood ILC.
format article
author Oisín Huhn
Martin A. Ivarsson
Lucy Gardner
Mike Hollinshead
Jane C Stinchcombe
Puran Chen
Norman Shreeve
Olympe Chazara
Lydia E. Farrell
Jakob Theorell
Hormas Ghadially
Peter Parham
Gillian Griffiths
Amir Horowitz
Ashley Moffett
Andrew M. Sharkey
Francesco Colucci
author_facet Oisín Huhn
Martin A. Ivarsson
Lucy Gardner
Mike Hollinshead
Jane C Stinchcombe
Puran Chen
Norman Shreeve
Olympe Chazara
Lydia E. Farrell
Jakob Theorell
Hormas Ghadially
Peter Parham
Gillian Griffiths
Amir Horowitz
Ashley Moffett
Andrew M. Sharkey
Francesco Colucci
author_sort Oisín Huhn
title Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
title_short Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
title_full Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
title_fullStr Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
title_full_unstemmed Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
title_sort distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/686fd2691411467caa9337f1f7add0f8
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