Depression and frailty in older adults: A population-based cohort study.

<h4>Background</h4>Studies have shown an association between depression and frailty, even though the literature has not reached a consensus regarding how these syndromes interact. Although prospective cohort studies on this topic are still scarce, they could contribute to understanding t...

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Autores principales:	Fabiana Araújo Figueiredo Da Mata, Marilia Miranda Forte Gomes, Jair Lício Ferreira Santos, Yeda Aparecida de Oliveira Duarte, Mauricio Gomes Pereira
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6870fabbee884ed086fc67c713e641c2
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spelling	oai:doaj.org-article:6870fabbee884ed086fc67c713e641c22021-11-25T06:23:47ZDepression and frailty in older adults: A population-based cohort study.1932-620310.1371/journal.pone.0247766https://doaj.org/article/6870fabbee884ed086fc67c713e641c22021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0247766https://doaj.org/toc/1932-6203<h4>Background</h4>Studies have shown an association between depression and frailty, even though the literature has not reached a consensus regarding how these syndromes interact. Although prospective cohort studies on this topic are still scarce, they could contribute to understanding this relationship. We aimed to observe whether depressive symptoms are risk factors for the onset of frailty among older adults living in São Paulo, Brazil.<h4>Methods</h4>Prospective cohort study using the "Health, Well-being and Aging" (SABE) Study databases of 2006 and 2010. The sample was representative of the community-dwelling older adults living in São Paulo, and it is composed of non-frail men and women aged 60 years and older without cognitive decline. We calculated the frailty incidence rate between older adults with and without depressive symptoms and calculated the incidence rate ratio. Multiple analysis was carried out through Poisson regression with robust variance estimation.<h4>Results</h4>The initial sample (n = 1,109) presented a mean age of 72 years (from 60 to 96) and 61.1% were women. The final sample was composed of 830 individuals, and the mean follow-up time in the study was 3.8 years. After adjusting the model, depressive symptoms did not predict the onset of frailty at follow-up.<h4>Conclusion</h4>Depressive symptoms were not shown to be a risk factor for frailty among older adults living in São Paulo in this study.Fabiana Araújo Figueiredo Da MataMarilia Miranda Forte GomesJair Lício Ferreira SantosYeda Aparecida de Oliveira DuarteMauricio Gomes PereiraPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 3, p e0247766 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fabiana Araújo Figueiredo Da Mata Marilia Miranda Forte Gomes Jair Lício Ferreira Santos Yeda Aparecida de Oliveira Duarte Mauricio Gomes Pereira Depression and frailty in older adults: A population-based cohort study.
description	<h4>Background</h4>Studies have shown an association between depression and frailty, even though the literature has not reached a consensus regarding how these syndromes interact. Although prospective cohort studies on this topic are still scarce, they could contribute to understanding this relationship. We aimed to observe whether depressive symptoms are risk factors for the onset of frailty among older adults living in São Paulo, Brazil.<h4>Methods</h4>Prospective cohort study using the "Health, Well-being and Aging" (SABE) Study databases of 2006 and 2010. The sample was representative of the community-dwelling older adults living in São Paulo, and it is composed of non-frail men and women aged 60 years and older without cognitive decline. We calculated the frailty incidence rate between older adults with and without depressive symptoms and calculated the incidence rate ratio. Multiple analysis was carried out through Poisson regression with robust variance estimation.<h4>Results</h4>The initial sample (n = 1,109) presented a mean age of 72 years (from 60 to 96) and 61.1% were women. The final sample was composed of 830 individuals, and the mean follow-up time in the study was 3.8 years. After adjusting the model, depressive symptoms did not predict the onset of frailty at follow-up.<h4>Conclusion</h4>Depressive symptoms were not shown to be a risk factor for frailty among older adults living in São Paulo in this study.
format	article
author	Fabiana Araújo Figueiredo Da Mata Marilia Miranda Forte Gomes Jair Lício Ferreira Santos Yeda Aparecida de Oliveira Duarte Mauricio Gomes Pereira
author_facet	Fabiana Araújo Figueiredo Da Mata Marilia Miranda Forte Gomes Jair Lício Ferreira Santos Yeda Aparecida de Oliveira Duarte Mauricio Gomes Pereira
author_sort	Fabiana Araújo Figueiredo Da Mata
title	Depression and frailty in older adults: A population-based cohort study.
title_short	Depression and frailty in older adults: A population-based cohort study.
title_full	Depression and frailty in older adults: A population-based cohort study.
title_fullStr	Depression and frailty in older adults: A population-based cohort study.
title_full_unstemmed	Depression and frailty in older adults: A population-based cohort study.
title_sort	depression and frailty in older adults: a population-based cohort study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/6870fabbee884ed086fc67c713e641c2
work_keys_str_mv	AT fabianaaraujofigueiredodamata depressionandfrailtyinolderadultsapopulationbasedcohortstudy AT mariliamirandafortegomes depressionandfrailtyinolderadultsapopulationbasedcohortstudy AT jairlicioferreirasantos depressionandfrailtyinolderadultsapopulationbasedcohortstudy AT yedaaparecidadeoliveiraduarte depressionandfrailtyinolderadultsapopulationbasedcohortstudy AT mauriciogomespereira depressionandfrailtyinolderadultsapopulationbasedcohortstudy
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Depression and frailty in older adults: A population-based cohort study.

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