Age-related hypogonadism in men with metabolic syndrome

Aim. To elucidate the relationship between testosterone and SSBG levels in men with age-related hypogonadism and metabolic syndrome. Materials and methods. The study included 125 men aged 30-80 years with a diagnosis of age-related hypogonadism. In all the cases, testosterone(T) and SSBG levels we...

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Autores principales: Yulia Alexandrovna Tishova, Georgy Zhiulievich Mskhalaya, Svetlana Yur'evna Kalinchenko
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2010
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Acceso en línea:https://doaj.org/article/68740b6b688b495eab145110cb1e12c8
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Sumario:Aim. To elucidate the relationship between testosterone and SSBG levels in men with age-related hypogonadism and metabolic syndrome. Materials and methods. The study included 125 men aged 30-80 years with a diagnosis of age-related hypogonadism. In all the cases, testosterone(T) and SSBG levels were determined, free T fraction calculated, and waist circumference measured. Almost half of the patients (n=56) presentedwith metabolic syndrome (MS) and underwent measurement of basal immunoreactive insulin (IRI). Results. Mean age of the patients (n=125) was 54 [46; 65] years, waist circumference 108 [102; 115] cm, total T 8.3 [5.9; 11] nmol/l (norm 12 -33.5), free T 140 [99.6; 184] pmol/l (norm