The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy

Abstract The Beijing Eye Study 2011 is a population-based cross-sectional study in Northern China, which enrolled 3468 participants whose age were more than 50 years. A detailed ophthalmic examination was performed including spectral-domain optical coherence tomography with enhanced depth imaging fo...

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Autores principales:	Lei Shao, Ling Xiao Zhou, Liang Xu, Wen Bin Wei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/68837d6fabca4849af3e717aac4492f7
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spelling	oai:doaj.org-article:68837d6fabca4849af3e717aac4492f72021-12-02T15:54:09ZThe relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy10.1038/s41598-021-84947-72045-2322https://doaj.org/article/68837d6fabca4849af3e717aac4492f72021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84947-7https://doaj.org/toc/2045-2322Abstract The Beijing Eye Study 2011 is a population-based cross-sectional study in Northern China, which enrolled 3468 participants whose age were more than 50 years. A detailed ophthalmic examination was performed including spectral-domain optical coherence tomography with enhanced depth imaging for measurement of SFCT and fundus photography. Blood pressure, fundus photographs and choroidal OCT-images were available for 3237 (93.3%) subjects, with 1953 (56.3 ± 0.8%) of the study population fulfilled the diagnosis of hypertension and 1089 subjects having hypertensive retinopathy. For the hypertensive cases, the SFCT in patients with hypertensive retinopathy (286.48 ± 105.23 µm) was significantly thicker than subjects without hypertensive retinopathy (187.04 ± 78.80 µm, P < 0.001). SFCT was significantly associated with the stage of hypertensive retinopathy (P < 0.001), but not significantly associated with diastolic blood pressure (P = 0.94), history (P = 0.95) and years (P = 0.91) of hypertension. In conclusion, hypertension as systemic disease was not significantly affect the subfoveal choroidal thickness, but as ocular disease, hypertensive retinopathy was significantly related to changes of choroidal thickness. Lesions of choroid during chronic hypertension may play an important role in development of hypertensive retinopathy.Lei ShaoLing Xiao ZhouLiang XuWen Bin WeiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lei Shao Ling Xiao Zhou Liang Xu Wen Bin Wei The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy
description	Abstract The Beijing Eye Study 2011 is a population-based cross-sectional study in Northern China, which enrolled 3468 participants whose age were more than 50 years. A detailed ophthalmic examination was performed including spectral-domain optical coherence tomography with enhanced depth imaging for measurement of SFCT and fundus photography. Blood pressure, fundus photographs and choroidal OCT-images were available for 3237 (93.3%) subjects, with 1953 (56.3 ± 0.8%) of the study population fulfilled the diagnosis of hypertension and 1089 subjects having hypertensive retinopathy. For the hypertensive cases, the SFCT in patients with hypertensive retinopathy (286.48 ± 105.23 µm) was significantly thicker than subjects without hypertensive retinopathy (187.04 ± 78.80 µm, P < 0.001). SFCT was significantly associated with the stage of hypertensive retinopathy (P < 0.001), but not significantly associated with diastolic blood pressure (P = 0.94), history (P = 0.95) and years (P = 0.91) of hypertension. In conclusion, hypertension as systemic disease was not significantly affect the subfoveal choroidal thickness, but as ocular disease, hypertensive retinopathy was significantly related to changes of choroidal thickness. Lesions of choroid during chronic hypertension may play an important role in development of hypertensive retinopathy.
format	article
author	Lei Shao Ling Xiao Zhou Liang Xu Wen Bin Wei
author_facet	Lei Shao Ling Xiao Zhou Liang Xu Wen Bin Wei
author_sort	Lei Shao
title	The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy
title_short	The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy
title_full	The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy
title_fullStr	The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy
title_full_unstemmed	The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy
title_sort	relationship between subfoveal choroidal thickness and hypertensive retinopathy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/68837d6fabca4849af3e717aac4492f7
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The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy

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