Single-cell RNA transcriptome reveals the intra-tumoral heterogeneity and regulators underlying tumor progression in metastatic pancreatic ductal adenocarcinoma
Abstract Pancreatic ductal adenocarcinoma (PDAC) is the most frequent and aggressive pancreatic tumor characterized by high metastatic risk and special tumor microenvironment. To comprehensively delineate the complex intra-tumoral heterogeneity and the underlying mechanism during metastatic lesions...
Enregistré dans:
Auteurs principaux: | Qianhui Xu, Shaohuai Chen, Yuanbo Hu, Wen Huang |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Publishing Group
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/689e994fd0f84f1ebf0b4b0d8b152230 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma
par: Jie Yang, et autres
Publié: (2021) -
Long non-coding RNA HOMER3-AS1 drives hepatocellular carcinoma progression via modulating the behaviors of both tumor cells and macrophages
par: Jian Pu, et autres
Publié: (2021) -
Gene transfection in primary stem-like cells of giant cell tumor of bone
par: Shalini Singh, et autres
Publié: (2010) -
ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling
par: Yuan He, et autres
Publié: (2021) -
Immune checkpoint inhibition for pancreatic ductal adenocarcinoma: limitations and prospects: a systematic review
par: Hong-Bo Li, et autres
Publié: (2021)