Single-cell RNA transcriptome reveals the intra-tumoral heterogeneity and regulators underlying tumor progression in metastatic pancreatic ductal adenocarcinoma

Abstract Pancreatic ductal adenocarcinoma (PDAC) is the most frequent and aggressive pancreatic tumor characterized by high metastatic risk and special tumor microenvironment. To comprehensively delineate the complex intra-tumoral heterogeneity and the underlying mechanism during metastatic lesions...

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Bibliographic Details
Main Authors: Qianhui Xu, Shaohuai Chen, Yuanbo Hu, Wen Huang
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/689e994fd0f84f1ebf0b4b0d8b152230
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