Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia

Objectives: To provide up-to-date data concerning hypertensive disorders of pregnancy on maternal and neonatal profiles in Indonesia. Methods: Retrospective clinical audit on all pregnancy-associated hypertensive women between 1 January 2020 and 31 March 2020 at Cianjur General District Hospital. Re...

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Autores principales:	Kevin Dominique Tjandraprawira, Aria Yusti Kusumah, Azka Yumna Kamilah, Dhini Isti Putri, Mayang Rizky Ananta, Selvi Puspa Sari, Tono Djuwantono, Aviva Petrie
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/68abc6e45c1c424a94e0922841c48358
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spelling	oai:doaj.org-article:68abc6e45c1c424a94e0922841c483582021-12-01T23:35:43ZManagement and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia2050-312110.1177/20503121211060194https://doaj.org/article/68abc6e45c1c424a94e0922841c483582021-11-01T00:00:00Zhttps://doi.org/10.1177/20503121211060194https://doaj.org/toc/2050-3121Objectives: To provide up-to-date data concerning hypertensive disorders of pregnancy on maternal and neonatal profiles in Indonesia. Methods: Retrospective clinical audit on all pregnancy-associated hypertensive women between 1 January 2020 and 31 March 2020 at Cianjur General District Hospital. Results: Preeclampsia accounts for 66.8% (235/352) of hypertensive disorders of pregnancy, gestational hypertension 29% (102/352) and chronic hypertension 4.3% (15/352). Compared to other pregnant women, those with preeclampsia, on average, had higher systolic and diastolic blood pressures and poorer kidney (ureum and creatinine) and liver function (aspartate transaminase enzyme and alanine transaminase enzyme) profiles (p < 0.001, < 0.001, < 0.001, 0.003, 0.033 and 0.002, respectively), and required more intensive care admission. Neonates from women with severe forms of preeclampsia (eclampsia and HELLP syndrome (haemolysis, elevated liver enzymes, low platelets)) had, on average, lower birthweight (p = 0.015 and 0.048, respectively) and birth length (p = 0.021, 0.017). Neonates from eclamptic mothers had poorer APGAR (appearance, pulse, grimace, activity and respiration) scores (p = 0.006 and 0.005, respectively). Conclusion: Hypertensive disorders of pregnancy exerts adverse maternal and neonatal outcomes, particularly among eclampsia and HELLP-syndrome neonates. Various challenges remain for optimal management.Kevin Dominique TjandraprawiraAria Yusti KusumahAzka Yumna KamilahDhini Isti PutriMayang Rizky AnantaSelvi Puspa SariTono DjuwantonoAviva PetrieSAGE PublishingarticleMedicine (General)R5-920ENSAGE Open Medicine, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Kevin Dominique Tjandraprawira Aria Yusti Kusumah Azka Yumna Kamilah Dhini Isti Putri Mayang Rizky Ananta Selvi Puspa Sari Tono Djuwantono Aviva Petrie Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia
description	Objectives: To provide up-to-date data concerning hypertensive disorders of pregnancy on maternal and neonatal profiles in Indonesia. Methods: Retrospective clinical audit on all pregnancy-associated hypertensive women between 1 January 2020 and 31 March 2020 at Cianjur General District Hospital. Results: Preeclampsia accounts for 66.8% (235/352) of hypertensive disorders of pregnancy, gestational hypertension 29% (102/352) and chronic hypertension 4.3% (15/352). Compared to other pregnant women, those with preeclampsia, on average, had higher systolic and diastolic blood pressures and poorer kidney (ureum and creatinine) and liver function (aspartate transaminase enzyme and alanine transaminase enzyme) profiles (p < 0.001, < 0.001, < 0.001, 0.003, 0.033 and 0.002, respectively), and required more intensive care admission. Neonates from women with severe forms of preeclampsia (eclampsia and HELLP syndrome (haemolysis, elevated liver enzymes, low platelets)) had, on average, lower birthweight (p = 0.015 and 0.048, respectively) and birth length (p = 0.021, 0.017). Neonates from eclamptic mothers had poorer APGAR (appearance, pulse, grimace, activity and respiration) scores (p = 0.006 and 0.005, respectively). Conclusion: Hypertensive disorders of pregnancy exerts adverse maternal and neonatal outcomes, particularly among eclampsia and HELLP-syndrome neonates. Various challenges remain for optimal management.
format	article
author	Kevin Dominique Tjandraprawira Aria Yusti Kusumah Azka Yumna Kamilah Dhini Isti Putri Mayang Rizky Ananta Selvi Puspa Sari Tono Djuwantono Aviva Petrie
author_facet	Kevin Dominique Tjandraprawira Aria Yusti Kusumah Azka Yumna Kamilah Dhini Isti Putri Mayang Rizky Ananta Selvi Puspa Sari Tono Djuwantono Aviva Petrie
author_sort	Kevin Dominique Tjandraprawira
title	Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia
title_short	Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia
title_full	Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia
title_fullStr	Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia
title_full_unstemmed	Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia
title_sort	management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in indonesia
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/68abc6e45c1c424a94e0922841c48358
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Management and perinatal outcomes of hypertensive disorders of pregnancy in a low-resource setting in Indonesia

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