JunB is essential for IL-23-dependent pathogenicity of Th17 cells

JunB is essential for IL-23-dependent pathogenicity of Th17 cells

T helper 17 (Th17) cells can be pathogenic, but what controls this phenotype is unclear. Here the authors show that the transcription factor JunB promotes proinflammatory Th17 function by regulating the transcription of multiple Th17-related genes.

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Detalles Bibliográficos
Autores principales: Zafrul Hasan, Shin-ichi Koizumi, Daiki Sasaki, Hayato Yamada, Nana Arakaki, Yoshitaka Fujihara, Shiho Okitsu, Hiroki Shirahata, Hiroki Ishikawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/68b10b31b4c2404e89ca812ba7589cc1
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