An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

Protein stability modulation by E3 ubiquitin ligases is an important layer of functional regulation, but screening for E3 ligase-substrate interactions is time-consuming and costly. Here, the authors take an in silico naïve Bayesian classifier approach to integrate multiple lines of evidence for E3-...

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Autores principales: Yang Li, Ping Xie, Liang Lu, Jian Wang, Lihong Diao, Zhongyang Liu, Feifei Guo, Yangzhige He, Yuan Liu, Qin Huang, Han Liang, Dong Li, Fuchu He
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/68c2fe0de1d34e4f89a3fa53d9ff21a4
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