Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection

Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 pr...

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Autores principales: Xiao-Lin Jiang, Guo-Lin Wang, Xiang-Na Zhao, Fei-Hu Yan, Lin Yao, Zeng-Qiang Kou, Sheng-Xiang Ji, Xiao-Li Zhang, Cun-Bao Li, Li-Jun Duan, Yan Li, Yu-Wen Zhang, Qing Duan, Tie-Cheng Wang, En-Tao Li, Xiao Wei, Qing-Yang Wang, Xue-Feng Wang, Wei-Yang Sun, Yu-Wei Gao, Dian-Min Kang, Ji-Yan Zhang, Mai-Juan Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/68c78fa7784c48cc8e87405a7f61c208
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Sumario:Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 proteins 3 months post-symptom onset, while IgM levels largely wane at this time.