Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 pr...
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Nature Portfolio
2021
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oai:doaj.org-article:68c78fa7784c48cc8e87405a7f61c2082021-12-02T13:30:15ZLasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection10.1038/s41467-021-21155-x2041-1723https://doaj.org/article/68c78fa7784c48cc8e87405a7f61c2082021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21155-xhttps://doaj.org/toc/2041-1723Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 proteins 3 months post-symptom onset, while IgM levels largely wane at this time.Xiao-Lin JiangGuo-Lin WangXiang-Na ZhaoFei-Hu YanLin YaoZeng-Qiang KouSheng-Xiang JiXiao-Li ZhangCun-Bao LiLi-Jun DuanYan LiYu-Wen ZhangQing DuanTie-Cheng WangEn-Tao LiXiao WeiQing-Yang WangXue-Feng WangWei-Yang SunYu-Wei GaoDian-Min KangJi-Yan ZhangMai-Juan MaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
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Science Q Xiao-Lin Jiang Guo-Lin Wang Xiang-Na Zhao Fei-Hu Yan Lin Yao Zeng-Qiang Kou Sheng-Xiang Ji Xiao-Li Zhang Cun-Bao Li Li-Jun Duan Yan Li Yu-Wen Zhang Qing Duan Tie-Cheng Wang En-Tao Li Xiao Wei Qing-Yang Wang Xue-Feng Wang Wei-Yang Sun Yu-Wei Gao Dian-Min Kang Ji-Yan Zhang Mai-Juan Ma Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection |
description |
Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 proteins 3 months post-symptom onset, while IgM levels largely wane at this time. |
format |
article |
author |
Xiao-Lin Jiang Guo-Lin Wang Xiang-Na Zhao Fei-Hu Yan Lin Yao Zeng-Qiang Kou Sheng-Xiang Ji Xiao-Li Zhang Cun-Bao Li Li-Jun Duan Yan Li Yu-Wen Zhang Qing Duan Tie-Cheng Wang En-Tao Li Xiao Wei Qing-Yang Wang Xue-Feng Wang Wei-Yang Sun Yu-Wei Gao Dian-Min Kang Ji-Yan Zhang Mai-Juan Ma |
author_facet |
Xiao-Lin Jiang Guo-Lin Wang Xiang-Na Zhao Fei-Hu Yan Lin Yao Zeng-Qiang Kou Sheng-Xiang Ji Xiao-Li Zhang Cun-Bao Li Li-Jun Duan Yan Li Yu-Wen Zhang Qing Duan Tie-Cheng Wang En-Tao Li Xiao Wei Qing-Yang Wang Xue-Feng Wang Wei-Yang Sun Yu-Wei Gao Dian-Min Kang Ji-Yan Zhang Mai-Juan Ma |
author_sort |
Xiao-Lin Jiang |
title |
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection |
title_short |
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection |
title_full |
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection |
title_fullStr |
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection |
title_full_unstemmed |
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection |
title_sort |
lasting antibody and t cell responses to sars-cov-2 in covid-19 patients three months after infection |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/68c78fa7784c48cc8e87405a7f61c208 |
work_keys_str_mv |
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