Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection

Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 pr...

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Autores principales: Xiao-Lin Jiang, Guo-Lin Wang, Xiang-Na Zhao, Fei-Hu Yan, Lin Yao, Zeng-Qiang Kou, Sheng-Xiang Ji, Xiao-Li Zhang, Cun-Bao Li, Li-Jun Duan, Yan Li, Yu-Wen Zhang, Qing Duan, Tie-Cheng Wang, En-Tao Li, Xiao Wei, Qing-Yang Wang, Xue-Feng Wang, Wei-Yang Sun, Yu-Wei Gao, Dian-Min Kang, Ji-Yan Zhang, Mai-Juan Ma
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/68c78fa7784c48cc8e87405a7f61c208
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spelling oai:doaj.org-article:68c78fa7784c48cc8e87405a7f61c2082021-12-02T13:30:15ZLasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection10.1038/s41467-021-21155-x2041-1723https://doaj.org/article/68c78fa7784c48cc8e87405a7f61c2082021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21155-xhttps://doaj.org/toc/2041-1723Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 proteins 3 months post-symptom onset, while IgM levels largely wane at this time.Xiao-Lin JiangGuo-Lin WangXiang-Na ZhaoFei-Hu YanLin YaoZeng-Qiang KouSheng-Xiang JiXiao-Li ZhangCun-Bao LiLi-Jun DuanYan LiYu-Wen ZhangQing DuanTie-Cheng WangEn-Tao LiXiao WeiQing-Yang WangXue-Feng WangWei-Yang SunYu-Wei GaoDian-Min KangJi-Yan ZhangMai-Juan MaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiao-Lin Jiang
Guo-Lin Wang
Xiang-Na Zhao
Fei-Hu Yan
Lin Yao
Zeng-Qiang Kou
Sheng-Xiang Ji
Xiao-Li Zhang
Cun-Bao Li
Li-Jun Duan
Yan Li
Yu-Wen Zhang
Qing Duan
Tie-Cheng Wang
En-Tao Li
Xiao Wei
Qing-Yang Wang
Xue-Feng Wang
Wei-Yang Sun
Yu-Wei Gao
Dian-Min Kang
Ji-Yan Zhang
Mai-Juan Ma
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
description Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 proteins 3 months post-symptom onset, while IgM levels largely wane at this time.
format article
author Xiao-Lin Jiang
Guo-Lin Wang
Xiang-Na Zhao
Fei-Hu Yan
Lin Yao
Zeng-Qiang Kou
Sheng-Xiang Ji
Xiao-Li Zhang
Cun-Bao Li
Li-Jun Duan
Yan Li
Yu-Wen Zhang
Qing Duan
Tie-Cheng Wang
En-Tao Li
Xiao Wei
Qing-Yang Wang
Xue-Feng Wang
Wei-Yang Sun
Yu-Wei Gao
Dian-Min Kang
Ji-Yan Zhang
Mai-Juan Ma
author_facet Xiao-Lin Jiang
Guo-Lin Wang
Xiang-Na Zhao
Fei-Hu Yan
Lin Yao
Zeng-Qiang Kou
Sheng-Xiang Ji
Xiao-Li Zhang
Cun-Bao Li
Li-Jun Duan
Yan Li
Yu-Wen Zhang
Qing Duan
Tie-Cheng Wang
En-Tao Li
Xiao Wei
Qing-Yang Wang
Xue-Feng Wang
Wei-Yang Sun
Yu-Wei Gao
Dian-Min Kang
Ji-Yan Zhang
Mai-Juan Ma
author_sort Xiao-Lin Jiang
title Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
title_short Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
title_full Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
title_fullStr Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
title_full_unstemmed Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
title_sort lasting antibody and t cell responses to sars-cov-2 in covid-19 patients three months after infection
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/68c78fa7784c48cc8e87405a7f61c208
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