COVID-2019–2020–2021: Systematic review and meta-analysis
Introduction: The world has faced the pandemic of COVID-19 in March 2020 and still it continues to affect in 2021. There is a great variation about the course of the disease and its features. Hence, in the present systemic review, we intend to determine the pooled estimations in the clinical feature...
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Wolters Kluwer Medknow Publications
2021
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oai:doaj.org-article:68cd24b027aa42969e80fd2ba0b0b5802021-11-19T12:15:51ZCOVID-2019–2020–2021: Systematic review and meta-analysis0975-740610.4103/jpbs.jpbs_371_21https://doaj.org/article/68cd24b027aa42969e80fd2ba0b0b5802021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=921;epage=926;aulast=Reddyhttps://doaj.org/toc/0975-7406Introduction: The world has faced the pandemic of COVID-19 in March 2020 and still it continues to affect in 2021. There is a great variation about the course of the disease and its features. Hence, in the present systemic review, we intend to determine the pooled estimations in the clinical features and prognosis along with the subgroups based on the severity of the disease in various regions of the world. Materials and Methods: Online data were collected from the search engines of EBSCO, PubMed, Google Scholar, and Scopus. The searched terms were COVID 19, CORONA, SARS-CoV-2, clinical features, Wuhan, etc. The study articles were collected that from January 2020 to February 2021. Based on the PRISMA guidelines, a meta-analysis was performed. Results: A total of 5067 articles were selected, of which 176 were finalized for the study. There were a total of 11 countries that were included, with a total of 2½ lakh participants. Mean age was 47.5 years. Around 22.5% had comorbidities. The mortality was 5.5%. We observed a strong association between the medical condition of the patient and the severity of the infection. In severe cases, the most common symptoms were respiratory and gastrointestinal. The mortality was registered in those with pneumonia and end-organ failure. Conclusion: It can be concluded from this meta-analysis that in a fourth of the positive patients, the disease was severe. In nearly 6% of the COVID-19 patients, mortality was seen. Patients with comorbidities and the severe form of the disease should be closely monitored.S Ganesh Kumar ReddyMaanini MantenaSameer Krishna Prasad GarlapatiB Prasanth ManoharHarpreet SinghKaran Singh BajwaHeena TiwariWolters Kluwer Medknow Publicationsarticleclinical featurescovid-19meta-analysisoutcomessystemic reviewPharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 921-926 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
clinical features covid-19 meta-analysis outcomes systemic review Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 |
| spellingShingle |
clinical features covid-19 meta-analysis outcomes systemic review Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 S Ganesh Kumar Reddy Maanini Mantena Sameer Krishna Prasad Garlapati B Prasanth Manohar Harpreet Singh Karan Singh Bajwa Heena Tiwari COVID-2019–2020–2021: Systematic review and meta-analysis |
| description |
Introduction: The world has faced the pandemic of COVID-19 in March 2020 and still it continues to affect in 2021. There is a great variation about the course of the disease and its features. Hence, in the present systemic review, we intend to determine the pooled estimations in the clinical features and prognosis along with the subgroups based on the severity of the disease in various regions of the world. Materials and Methods: Online data were collected from the search engines of EBSCO, PubMed, Google Scholar, and Scopus. The searched terms were COVID 19, CORONA, SARS-CoV-2, clinical features, Wuhan, etc. The study articles were collected that from January 2020 to February 2021. Based on the PRISMA guidelines, a meta-analysis was performed. Results: A total of 5067 articles were selected, of which 176 were finalized for the study. There were a total of 11 countries that were included, with a total of 2½ lakh participants. Mean age was 47.5 years. Around 22.5% had comorbidities. The mortality was 5.5%. We observed a strong association between the medical condition of the patient and the severity of the infection. In severe cases, the most common symptoms were respiratory and gastrointestinal. The mortality was registered in those with pneumonia and end-organ failure. Conclusion: It can be concluded from this meta-analysis that in a fourth of the positive patients, the disease was severe. In nearly 6% of the COVID-19 patients, mortality was seen. Patients with comorbidities and the severe form of the disease should be closely monitored. |
| format |
article |
| author |
S Ganesh Kumar Reddy Maanini Mantena Sameer Krishna Prasad Garlapati B Prasanth Manohar Harpreet Singh Karan Singh Bajwa Heena Tiwari |
| author_facet |
S Ganesh Kumar Reddy Maanini Mantena Sameer Krishna Prasad Garlapati B Prasanth Manohar Harpreet Singh Karan Singh Bajwa Heena Tiwari |
| author_sort |
S Ganesh Kumar Reddy |
| title |
COVID-2019–2020–2021: Systematic review and meta-analysis |
| title_short |
COVID-2019–2020–2021: Systematic review and meta-analysis |
| title_full |
COVID-2019–2020–2021: Systematic review and meta-analysis |
| title_fullStr |
COVID-2019–2020–2021: Systematic review and meta-analysis |
| title_full_unstemmed |
COVID-2019–2020–2021: Systematic review and meta-analysis |
| title_sort |
covid-2019–2020–2021: systematic review and meta-analysis |
| publisher |
Wolters Kluwer Medknow Publications |
| publishDate |
2021 |
| url |
https://doaj.org/article/68cd24b027aa42969e80fd2ba0b0b580 |
| work_keys_str_mv |
AT sganeshkumarreddy covid201920202021systematicreviewandmetaanalysis AT maaninimantena covid201920202021systematicreviewandmetaanalysis AT sameerkrishnaprasadgarlapati covid201920202021systematicreviewandmetaanalysis AT bprasanthmanohar covid201920202021systematicreviewandmetaanalysis AT harpreetsingh covid201920202021systematicreviewandmetaanalysis AT karansinghbajwa covid201920202021systematicreviewandmetaanalysis AT heenatiwari covid201920202021systematicreviewandmetaanalysis |
| _version_ |
1718420136397897728 |