Cooperative tumour cell membrane targeted phototherapy

Tumour distribution of targeted therapies is intrinsically heterogeneous. Here, the authors develop a strategy to decorate entire tumour membranes with synthetic receptors for amplified targeting of therapeutics and show that such cooperative membrane-targeted phototherapy results in tumour regressi...

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Autores principales: Heegon Kim, Junsung Lee, Chanhee Oh, Ji-Ho Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/68d64138a189430098d80c9c59fba732
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spelling oai:doaj.org-article:68d64138a189430098d80c9c59fba7322021-12-02T14:41:19ZCooperative tumour cell membrane targeted phototherapy10.1038/ncomms158802041-1723https://doaj.org/article/68d64138a189430098d80c9c59fba7322017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15880https://doaj.org/toc/2041-1723Tumour distribution of targeted therapies is intrinsically heterogeneous. Here, the authors develop a strategy to decorate entire tumour membranes with synthetic receptors for amplified targeting of therapeutics and show that such cooperative membrane-targeted phototherapy results in tumour regression in mice.Heegon KimJunsung LeeChanhee OhJi-Ho ParkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Heegon Kim
Junsung Lee
Chanhee Oh
Ji-Ho Park
Cooperative tumour cell membrane targeted phototherapy
description Tumour distribution of targeted therapies is intrinsically heterogeneous. Here, the authors develop a strategy to decorate entire tumour membranes with synthetic receptors for amplified targeting of therapeutics and show that such cooperative membrane-targeted phototherapy results in tumour regression in mice.
format article
author Heegon Kim
Junsung Lee
Chanhee Oh
Ji-Ho Park
author_facet Heegon Kim
Junsung Lee
Chanhee Oh
Ji-Ho Park
author_sort Heegon Kim
title Cooperative tumour cell membrane targeted phototherapy
title_short Cooperative tumour cell membrane targeted phototherapy
title_full Cooperative tumour cell membrane targeted phototherapy
title_fullStr Cooperative tumour cell membrane targeted phototherapy
title_full_unstemmed Cooperative tumour cell membrane targeted phototherapy
title_sort cooperative tumour cell membrane targeted phototherapy
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/68d64138a189430098d80c9c59fba732
work_keys_str_mv AT heegonkim cooperativetumourcellmembranetargetedphototherapy
AT junsunglee cooperativetumourcellmembranetargetedphototherapy
AT chanheeoh cooperativetumourcellmembranetargetedphototherapy
AT jihopark cooperativetumourcellmembranetargetedphototherapy
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