Atom-economic catalytic amide synthesis from amines and carboxylic acids activated in situ with acetylenes
Amide formation is a ubiquitous reaction in organic chemistry, but suffers from the problem of generating large amounts of waste. Here, the authors report a catalytic amide synthesis by the ruthenium catalysed addition of carboxylic acids to acetylenes, followed by reaction with primary or secondary...
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Autores principales: | Thilo Krause, Sabrina Baader, Benjamin Erb, Lukas J. Gooßen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/68da9c19f6924ffc9968ed44e9e56cf5 |
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