Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection

The antibody response during infection with dengue virus is a key component involved in the pathogenesis during secondary infection. Here the authors show antibodies targeting NS1 and the epitopes targeted can be associated with disease severity during human infection.

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Autores principales:	Deshni Jayathilaka, Laksiri Gomes, Chandima Jeewandara, Geethal. S. Bandara Jayarathna, Dhanushka Herath, Pathum Asela Perera, Samitha Fernando, Ananda Wijewickrama, Clare S. Hardman, Graham S. Ogg, Gathsaurie Neelika Malavige
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/68e71681d54c4d23a58d50624975f5e5
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spelling	oai:doaj.org-article:68e71681d54c4d23a58d50624975f5e52021-12-02T15:33:56ZRole of NS1 antibodies in the pathogenesis of acute secondary dengue infection10.1038/s41467-018-07667-z2041-1723https://doaj.org/article/68e71681d54c4d23a58d50624975f5e52018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07667-zhttps://doaj.org/toc/2041-1723The antibody response during infection with dengue virus is a key component involved in the pathogenesis during secondary infection. Here the authors show antibodies targeting NS1 and the epitopes targeted can be associated with disease severity during human infection.Deshni JayathilakaLaksiri GomesChandima JeewandaraGeethal. S. Bandara JayarathnaDhanushka HerathPathum Asela PereraSamitha FernandoAnanda WijewickramaClare S. HardmanGraham S. OggGathsaurie Neelika MalavigeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Deshni Jayathilaka Laksiri Gomes Chandima Jeewandara Geethal. S. Bandara Jayarathna Dhanushka Herath Pathum Asela Perera Samitha Fernando Ananda Wijewickrama Clare S. Hardman Graham S. Ogg Gathsaurie Neelika Malavige Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
description	The antibody response during infection with dengue virus is a key component involved in the pathogenesis during secondary infection. Here the authors show antibodies targeting NS1 and the epitopes targeted can be associated with disease severity during human infection.
format	article
author	Deshni Jayathilaka Laksiri Gomes Chandima Jeewandara Geethal. S. Bandara Jayarathna Dhanushka Herath Pathum Asela Perera Samitha Fernando Ananda Wijewickrama Clare S. Hardman Graham S. Ogg Gathsaurie Neelika Malavige
author_facet	Deshni Jayathilaka Laksiri Gomes Chandima Jeewandara Geethal. S. Bandara Jayarathna Dhanushka Herath Pathum Asela Perera Samitha Fernando Ananda Wijewickrama Clare S. Hardman Graham S. Ogg Gathsaurie Neelika Malavige
author_sort	Deshni Jayathilaka
title	Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
title_short	Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
title_full	Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
title_fullStr	Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
title_full_unstemmed	Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection
title_sort	role of ns1 antibodies in the pathogenesis of acute secondary dengue infection
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/68e71681d54c4d23a58d50624975f5e5
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Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection

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