Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Influenza A viruses can adapt to new host species, leading to the emergence of novel pathogenic strains. There is evidence that highly pathogenic viruses encode for non-structural 1 (NS1) proteins that are more efficient in suppressing the host immune response. The NS1 protein inhibits type-I interf...

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Autores principales: Ricardo Rajsbaum, Randy A Albrecht, May K Wang, Natalya P Maharaj, Gijs A Versteeg, Estanislao Nistal-Villán, Adolfo García-Sastre, Michaela U Gack
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/68e798ffdedb4154898c30314604fbb4
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