Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome

Stem cells exert their beneficial effects through secretion of regenerative factors. Here, the authors take the membranes and secreted factors from cardiac stem cells and generate a synthetic cell-mimicking microparticle, which, on injection in a mouse model of myocardial infarction, improves cardia...

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Autores principales:	Junnan Tang, Deliang Shen, Thomas George Caranasos, Zegen Wang, Adam C. Vandergriff, Tyler A. Allen, Michael Taylor Hensley, Phuong-Uyen Dinh, Jhon Cores, Tao-Sheng Li, Jinying Zhang, Quancheng Kan, Ke Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/68e90f01537b4132b5e027e02c99e7f0
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spelling	oai:doaj.org-article:68e90f01537b4132b5e027e02c99e7f02021-12-02T14:41:22ZTherapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome10.1038/ncomms137242041-1723https://doaj.org/article/68e90f01537b4132b5e027e02c99e7f02017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13724https://doaj.org/toc/2041-1723Stem cells exert their beneficial effects through secretion of regenerative factors. Here, the authors take the membranes and secreted factors from cardiac stem cells and generate a synthetic cell-mimicking microparticle, which, on injection in a mouse model of myocardial infarction, improves cardiac function.Junnan TangDeliang ShenThomas George CaranasosZegen WangAdam C. VandergriffTyler A. AllenMichael Taylor HensleyPhuong-Uyen DinhJhon CoresTao-Sheng LiJinying ZhangQuancheng KanKe ChengNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Junnan Tang Deliang Shen Thomas George Caranasos Zegen Wang Adam C. Vandergriff Tyler A. Allen Michael Taylor Hensley Phuong-Uyen Dinh Jhon Cores Tao-Sheng Li Jinying Zhang Quancheng Kan Ke Cheng Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
description	Stem cells exert their beneficial effects through secretion of regenerative factors. Here, the authors take the membranes and secreted factors from cardiac stem cells and generate a synthetic cell-mimicking microparticle, which, on injection in a mouse model of myocardial infarction, improves cardiac function.
format	article
author	Junnan Tang Deliang Shen Thomas George Caranasos Zegen Wang Adam C. Vandergriff Tyler A. Allen Michael Taylor Hensley Phuong-Uyen Dinh Jhon Cores Tao-Sheng Li Jinying Zhang Quancheng Kan Ke Cheng
author_facet	Junnan Tang Deliang Shen Thomas George Caranasos Zegen Wang Adam C. Vandergriff Tyler A. Allen Michael Taylor Hensley Phuong-Uyen Dinh Jhon Cores Tao-Sheng Li Jinying Zhang Quancheng Kan Ke Cheng
author_sort	Junnan Tang
title	Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
title_short	Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
title_full	Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
title_fullStr	Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
title_full_unstemmed	Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
title_sort	therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/68e90f01537b4132b5e027e02c99e7f0
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_version_	1718389934316847104

Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome

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