Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease.

Toll-like receptors (TLRs) participate in the defence against bacterial infections that are common in patients with Chronic Obstructive Pulmonary Disease (COPD). We studied all tagging SNPs in TLR2 and TLR4 and their associations with the level and change over time of both FEV(1) and sputum inflamma...

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Autores principales: Simona E Budulac, H Marike Boezen, Pieter S Hiemstra, Therese S Lapperre, Judith M Vonk, Wim Timens, Dirkje S Postma, GLUCOLD study group
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/68f893757b8d48599b02d4cca28da0af
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