Synthesis, anti-tubercular evaluation and molecular docking studies of Nitrogen-rich piperazine-pyrimidine-pyrazole Hybrid Motifs
A convenient and efficient synthesis of a series of ethyl-1-(6-(4-substitutedacetylatedpiperazin-1-yl)pyrimidin-4-yl)-5-amino-1H-pyrazole-4-carboxylate (8a-8j) has been developed by five steps which include activation of a methylene group, hydrazinolysis, cyclisation and chloro-amine coupli...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Growing Science
2022
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| Subjects: | |
| Online Access: | https://doaj.org/article/68fa9342f10b4e0aa53919312e627df7 |
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