The genetic basis for the adaptation of E. coli to sugar synthesis from CO2

An E. coli strain able to use CO2 fixation for sugar synthesis was previously generated by experimental evolution of an engineered strain. Here, Herz et al. show that specific mutations in five genes, encoding carbon metabolism enzymes or key regulators, are sufficient to enable robust growth of the...

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Autores principales:	Elad Herz, Niv Antonovsky, Yinon Bar-On, Dan Davidi, Shmuel Gleizer, Noam Prywes, Lianet Noda-Garcia, Keren Lyn Frisch, Yehudit Zohar, David G. Wernick, Alon Savidor, Uri Barenholz, Ron Milo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/690248970691410cad98d1f38c3b74f9
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spelling	oai:doaj.org-article:690248970691410cad98d1f38c3b74f92021-12-02T16:51:42ZThe genetic basis for the adaptation of E. coli to sugar synthesis from CO210.1038/s41467-017-01835-32041-1723https://doaj.org/article/690248970691410cad98d1f38c3b74f92017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01835-3https://doaj.org/toc/2041-1723An E. coli strain able to use CO2 fixation for sugar synthesis was previously generated by experimental evolution of an engineered strain. Here, Herz et al. show that specific mutations in five genes, encoding carbon metabolism enzymes or key regulators, are sufficient to enable robust growth of the strain.Elad HerzNiv AntonovskyYinon Bar-OnDan DavidiShmuel GleizerNoam PrywesLianet Noda-GarciaKeren Lyn FrischYehudit ZoharDavid G. WernickAlon SavidorUri BarenholzRon MiloNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elad Herz Niv Antonovsky Yinon Bar-On Dan Davidi Shmuel Gleizer Noam Prywes Lianet Noda-Garcia Keren Lyn Frisch Yehudit Zohar David G. Wernick Alon Savidor Uri Barenholz Ron Milo The genetic basis for the adaptation of E. coli to sugar synthesis from CO2
description	An E. coli strain able to use CO2 fixation for sugar synthesis was previously generated by experimental evolution of an engineered strain. Here, Herz et al. show that specific mutations in five genes, encoding carbon metabolism enzymes or key regulators, are sufficient to enable robust growth of the strain.
format	article
author	Elad Herz Niv Antonovsky Yinon Bar-On Dan Davidi Shmuel Gleizer Noam Prywes Lianet Noda-Garcia Keren Lyn Frisch Yehudit Zohar David G. Wernick Alon Savidor Uri Barenholz Ron Milo
author_facet	Elad Herz Niv Antonovsky Yinon Bar-On Dan Davidi Shmuel Gleizer Noam Prywes Lianet Noda-Garcia Keren Lyn Frisch Yehudit Zohar David G. Wernick Alon Savidor Uri Barenholz Ron Milo
author_sort	Elad Herz
title	The genetic basis for the adaptation of E. coli to sugar synthesis from CO2
title_short	The genetic basis for the adaptation of E. coli to sugar synthesis from CO2
title_full	The genetic basis for the adaptation of E. coli to sugar synthesis from CO2
title_fullStr	The genetic basis for the adaptation of E. coli to sugar synthesis from CO2
title_full_unstemmed	The genetic basis for the adaptation of E. coli to sugar synthesis from CO2
title_sort	genetic basis for the adaptation of e. coli to sugar synthesis from co2
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/690248970691410cad98d1f38c3b74f9
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The genetic basis for the adaptation of E. coli to sugar synthesis from CO2

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