The genetic basis for the adaptation of E. coli to sugar synthesis from CO2

An E. coli strain able to use CO2 fixation for sugar synthesis was previously generated by experimental evolution of an engineered strain. Here, Herz et al. show that specific mutations in five genes, encoding carbon metabolism enzymes or key regulators, are sufficient to enable robust growth of the...

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Main Authors: Elad Herz, Niv Antonovsky, Yinon Bar-On, Dan Davidi, Shmuel Gleizer, Noam Prywes, Lianet Noda-Garcia, Keren Lyn Frisch, Yehudit Zohar, David G. Wernick, Alon Savidor, Uri Barenholz, Ron Milo
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/690248970691410cad98d1f38c3b74f9
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