Growth factors in the treatment of diabetic foot syndrome

Growth factors play a key role in wound healing, deficiency of which leads to delayed healing. Various growth factors are used in the treatment of chronic wounds, including diabetic foot ulcers. The purpose of this review was to analyse the literature data on the effectiveness of epidermal growth fa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elena Y. Komelyagina, Michail B. Antsiferov
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2019
Materias:	diabetes mellitus diabetic foot syndrome growth factors epidermal growth factor platelet-rich plasma platelet growth factor Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/6921a2bddab642e9bcd0fe30cc3f5179
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6921a2bddab642e9bcd0fe30cc3f5179
record_format	dspace
spelling	oai:doaj.org-article:6921a2bddab642e9bcd0fe30cc3f51792021-11-14T09:00:22ZGrowth factors in the treatment of diabetic foot syndrome2072-03512072-037810.14341/DM10130https://doaj.org/article/6921a2bddab642e9bcd0fe30cc3f51792019-10-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/10130https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Growth factors play a key role in wound healing, deficiency of which leads to delayed healing. Various growth factors are used in the treatment of chronic wounds, including diabetic foot ulcers. The purpose of this review was to analyse the literature data on the effectiveness of epidermal growth factor, platelet-rich plasma and platelet growth factor in patients with diabetic foot syndrome. The effect of treatment with these growth factors on healing of diabetic foot ulcers and healing time were analysed. Published studies, mostly with low level of evidence, demonstrate a positive effect of various growth factors on the healing process of diabetic foot ulcers. Currently, there is no conclusion on the advantages of growth factor therapy. Further studies with a high level of evidence are needed to justify their use in routine clinical practice.Elena Y. KomelyaginaMichail B. AntsiferovEndocrinology Research Centrearticlediabetes mellitusdiabetic foot syndromegrowth factorsepidermal growth factorplatelet-rich plasmaplatelet growth factorNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 22, Iss 4, Pp 377-383 (2019)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus diabetic foot syndrome growth factors epidermal growth factor platelet-rich plasma platelet growth factor Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus diabetic foot syndrome growth factors epidermal growth factor platelet-rich plasma platelet growth factor Nutritional diseases. Deficiency diseases RC620-627 Elena Y. Komelyagina Michail B. Antsiferov Growth factors in the treatment of diabetic foot syndrome
description	Growth factors play a key role in wound healing, deficiency of which leads to delayed healing. Various growth factors are used in the treatment of chronic wounds, including diabetic foot ulcers. The purpose of this review was to analyse the literature data on the effectiveness of epidermal growth factor, platelet-rich plasma and platelet growth factor in patients with diabetic foot syndrome. The effect of treatment with these growth factors on healing of diabetic foot ulcers and healing time were analysed. Published studies, mostly with low level of evidence, demonstrate a positive effect of various growth factors on the healing process of diabetic foot ulcers. Currently, there is no conclusion on the advantages of growth factor therapy. Further studies with a high level of evidence are needed to justify their use in routine clinical practice.
format	article
author	Elena Y. Komelyagina Michail B. Antsiferov
author_facet	Elena Y. Komelyagina Michail B. Antsiferov
author_sort	Elena Y. Komelyagina
title	Growth factors in the treatment of diabetic foot syndrome
title_short	Growth factors in the treatment of diabetic foot syndrome
title_full	Growth factors in the treatment of diabetic foot syndrome
title_fullStr	Growth factors in the treatment of diabetic foot syndrome
title_full_unstemmed	Growth factors in the treatment of diabetic foot syndrome
title_sort	growth factors in the treatment of diabetic foot syndrome
publisher	Endocrinology Research Centre
publishDate	2019
url	https://doaj.org/article/6921a2bddab642e9bcd0fe30cc3f5179
work_keys_str_mv	AT elenaykomelyagina growthfactorsinthetreatmentofdiabeticfootsyndrome AT michailbantsiferov growthfactorsinthetreatmentofdiabeticfootsyndrome
_version_	1718429534770954240

Growth factors in the treatment of diabetic foot syndrome

Ejemplares similares