Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

Hybridomas are widely used for antibody screening and production due to their genetic stability and rapid proliferation. Here the authors demonstrate the rapid reprogramming of antibody specificity in hybridomas using CRISPR-Cas9.

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Detalles Bibliográficos
Autores principales:	Mark Pogson, Cristina Parola, William J. Kelton, Paul Heuberger, Sai T. Reddy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6925af93eca14d3ca5ad753540c1ac3f
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spelling	oai:doaj.org-article:6925af93eca14d3ca5ad753540c1ac3f2021-12-02T14:39:54ZImmunogenomic engineering of a plug-and-(dis)play hybridoma platform10.1038/ncomms125352041-1723https://doaj.org/article/6925af93eca14d3ca5ad753540c1ac3f2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12535https://doaj.org/toc/2041-1723Hybridomas are widely used for antibody screening and production due to their genetic stability and rapid proliferation. Here the authors demonstrate the rapid reprogramming of antibody specificity in hybridomas using CRISPR-Cas9.Mark PogsonCristina ParolaWilliam J. KeltonPaul HeubergerSai T. ReddyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mark Pogson Cristina Parola William J. Kelton Paul Heuberger Sai T. Reddy Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
description	Hybridomas are widely used for antibody screening and production due to their genetic stability and rapid proliferation. Here the authors demonstrate the rapid reprogramming of antibody specificity in hybridomas using CRISPR-Cas9.
format	article
author	Mark Pogson Cristina Parola William J. Kelton Paul Heuberger Sai T. Reddy
author_facet	Mark Pogson Cristina Parola William J. Kelton Paul Heuberger Sai T. Reddy
author_sort	Mark Pogson
title	Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
title_short	Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
title_full	Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
title_fullStr	Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
title_full_unstemmed	Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
title_sort	immunogenomic engineering of a plug-and-(dis)play hybridoma platform
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6925af93eca14d3ca5ad753540c1ac3f
work_keys_str_mv	AT markpogson immunogenomicengineeringofapluganddisplayhybridomaplatform AT cristinaparola immunogenomicengineeringofapluganddisplayhybridomaplatform AT williamjkelton immunogenomicengineeringofapluganddisplayhybridomaplatform AT paulheuberger immunogenomicengineeringofapluganddisplayhybridomaplatform AT saitreddy immunogenomicengineeringofapluganddisplayhybridomaplatform
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Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

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