Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
Hybridomas are widely used for antibody screening and production due to their genetic stability and rapid proliferation. Here the authors demonstrate the rapid reprogramming of antibody specificity in hybridomas using CRISPR-Cas9.
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Autores principales: | Mark Pogson, Cristina Parola, William J. Kelton, Paul Heuberger, Sai T. Reddy |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/6925af93eca14d3ca5ad753540c1ac3f |
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