Oral contraceptive consumption and cerebral venous sinuses thrombosis

Introduction: Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke and the clinical presentation is variable. One of the more common acquired risk factors of venous sinus thrombosis is oral contraceptive medications. While the prognosis for CVST is favorable, it is important to identif...

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Autores principales:	Jha Gupta Kukum, Jha Rajiv
Formato:	article
Lenguaje:	EN
Publicado:	Society of Surgeons of Nepal 2016
Materias:	Cerebral Venous sinus Thrombosis (CVST) Heparin OCP (Oral Contraceptive pills) Surgery RD1-811
Acceso en línea:	https://doaj.org/article/6937a4b820654ff88ecb8eb6a0bf680c
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spelling	oai:doaj.org-article:6937a4b820654ff88ecb8eb6a0bf680c2021-12-05T19:16:49ZOral contraceptive consumption and cerebral venous sinuses thrombosis10.3126/jssn.v17i1.151731815-39842392-4772https://doaj.org/article/6937a4b820654ff88ecb8eb6a0bf680c2016-07-01T00:00:00Zhttps://www.nepjol.info/index.php/JSSN/article/view/15173https://doaj.org/toc/1815-3984https://doaj.org/toc/2392-4772 Introduction: Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke and the clinical presentation is variable. One of the more common acquired risk factors of venous sinus thrombosis is oral contraceptive medications. While the prognosis for CVST is favorable, it is important to identify and treat early to prevent neurologic deficits. CVST accounts for 0.5% of strokes and most commonly presents with headaches and in many cases focal neurologic deficits. Diagnosis is confirmed with neuroimaging including CT angiography or MR angiography. Treatment consists of anticoagulation and in some cases, thrombolytic therapy is beneficial. The overall prognosis of CVST is favorable. The objective of the study is to describe the features of a series of patient with CVST due to consumption of OCPs, treated in the department of Neurosurgery, Bir hospital and OM hospital, and to discuss the risk factors associated with consumption of OCPs, its presentation, and outcome. Methods: This is a retrospective case series carried out in the department of Neurosurgery, Bir hospital and OM hospital during the year September 2012 to September 2014. Demographic features like age, presenting symptoms, clinical findings and outcome were analyzed. All cases received heparin or LMWH followed by Warfarin. Results: Nine patients were identified over a period of 2 years. The presenting symptoms included headache, vomiting, loss of consciousness, focal neurological deficit, seizure and neck pain. Signs found included papilloedema, fever, slurring of speech and focal neurological signs. Conclusion: Dural sinus thrombosis is a rare and under-recognized cause of headache that should be considered in women with recent introduction of hormonal contraception. The absence of papilledema and a negative CT brain should not halt further workup. MRI/venogram is mandatory to confirm the diagnosis. Journal of Society of Surgeons of Nepal Vol.17(1) 2014: 2-5 Jha Gupta KukumJha RajivSociety of Surgeons of NepalarticleCerebral Venous sinus Thrombosis (CVST)HeparinOCP (Oral Contraceptive pills)SurgeryRD1-811ENJournal of Society of Surgeons of Nepal, Vol 17, Iss 1 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cerebral Venous sinus Thrombosis (CVST) Heparin OCP (Oral Contraceptive pills) Surgery RD1-811
spellingShingle	Cerebral Venous sinus Thrombosis (CVST) Heparin OCP (Oral Contraceptive pills) Surgery RD1-811 Jha Gupta Kukum Jha Rajiv Oral contraceptive consumption and cerebral venous sinuses thrombosis
description	Introduction: Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke and the clinical presentation is variable. One of the more common acquired risk factors of venous sinus thrombosis is oral contraceptive medications. While the prognosis for CVST is favorable, it is important to identify and treat early to prevent neurologic deficits. CVST accounts for 0.5% of strokes and most commonly presents with headaches and in many cases focal neurologic deficits. Diagnosis is confirmed with neuroimaging including CT angiography or MR angiography. Treatment consists of anticoagulation and in some cases, thrombolytic therapy is beneficial. The overall prognosis of CVST is favorable. The objective of the study is to describe the features of a series of patient with CVST due to consumption of OCPs, treated in the department of Neurosurgery, Bir hospital and OM hospital, and to discuss the risk factors associated with consumption of OCPs, its presentation, and outcome. Methods: This is a retrospective case series carried out in the department of Neurosurgery, Bir hospital and OM hospital during the year September 2012 to September 2014. Demographic features like age, presenting symptoms, clinical findings and outcome were analyzed. All cases received heparin or LMWH followed by Warfarin. Results: Nine patients were identified over a period of 2 years. The presenting symptoms included headache, vomiting, loss of consciousness, focal neurological deficit, seizure and neck pain. Signs found included papilloedema, fever, slurring of speech and focal neurological signs. Conclusion: Dural sinus thrombosis is a rare and under-recognized cause of headache that should be considered in women with recent introduction of hormonal contraception. The absence of papilledema and a negative CT brain should not halt further workup. MRI/venogram is mandatory to confirm the diagnosis. Journal of Society of Surgeons of Nepal Vol.17(1) 2014: 2-5
format	article
author	Jha Gupta Kukum Jha Rajiv
author_facet	Jha Gupta Kukum Jha Rajiv
author_sort	Jha Gupta Kukum
title	Oral contraceptive consumption and cerebral venous sinuses thrombosis
title_short	Oral contraceptive consumption and cerebral venous sinuses thrombosis
title_full	Oral contraceptive consumption and cerebral venous sinuses thrombosis
title_fullStr	Oral contraceptive consumption and cerebral venous sinuses thrombosis
title_full_unstemmed	Oral contraceptive consumption and cerebral venous sinuses thrombosis
title_sort	oral contraceptive consumption and cerebral venous sinuses thrombosis
publisher	Society of Surgeons of Nepal
publishDate	2016
url	https://doaj.org/article/6937a4b820654ff88ecb8eb6a0bf680c
work_keys_str_mv	AT jhaguptakukum oralcontraceptiveconsumptionandcerebralvenoussinusesthrombosis AT jharajiv oralcontraceptiveconsumptionandcerebralvenoussinusesthrombosis
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Oral contraceptive consumption and cerebral venous sinuses thrombosis

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